Evolving Paradigms in Sepsis Management: A Narrative Review
Min-Ji Kim,
Eun-Joo Choi,
Eun-Jung Choi
Abstract:Sepsis, a condition characterized by life-threatening organ dysfunction due to a dysregulated host response to infection, significantly impacts global health, with mortality rates varying widely across regions. Traditional therapeutic strategies that target hyperinflammation and immunosuppression have largely failed to improve outcomes, underscoring the need for innovative approaches. This review examines the development of therapeutic agents for sepsis, with a focus on clinical trials addressing hyperinflamma… Show more
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