Evolving alterations of structural organization and functional connectivity in feedforward neural networks after induced P301L tau mutation
Janelle S. Weir,
Katrine Sjaastad Hanssen,
Nicolai Winter-Hjelm
et al.
Abstract:Reciprocal structure-function relationships underly both healthy and pathological behaviors in complex neural networks. Neuropathology can have widespread implications on the structural properties of neural networks, and drive changes in the functional interactions among network components at the micro-, and mesoscale level. Thus, understanding network dysfunction requires a thorough investigation of the complex interactions between structural and functional network reconfigurations in response to perturbation… Show more
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