Evolution of the Research Literature and the Scientific Community of Alzheimer’s Disease from 1983-2017: A 35-Year Survey

Robert, Claude; Wilson, Concepción S.; Lipton, Richard B.; Arreto, Charles Daniel

doi:10.3233/jad-191281

Cited by 3 publications

(1 citation statement)

References 131 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Through investigation, the number of students participating in tennis has increased year by year. Now college tennis has shown a thriving scene, the prospect of tennis is unlimited [5][6]. In college tennis teaching, the communication between teachers and students can fully reflect the artistry of language use in teaching, which provides a new perspective for the theoretical research of sports teaching [7][8].…”

Section: Introductionmentioning

confidence: 99%

University Tennis Teaching and Scientific Research Documents under the Background of Big Data

2021

IJECMR

View full text Add to dashboard Cite

With the advent of the era of big data, a brand-new vision and broad thinking have been provided for the evaluation of college physical education teaching. This article mainly studies the analysis of college tennis teaching scientific research literature under the background of big data. In order to ensure the credibility of the survey content, the retest method was used to test the reliability of the questionnaire during the survey. Thirty students in the public sports tennis class were selected, and the same questionnaire was distributed and tested at intervals of 2 weeks. After the recovery, the correlation analysis with the previous questionnaire was carried out. This article uses SPSS17 statistical software to perform mathematical statistics on the experimental results. Among them, the independent sample T test is mainly used to carry out mathematical statistics on the cultural class scores and motor skills assessment after the experiment. The statistical results include the average score, standard deviation, variance between groups (F) and coefficient significance test (sig). The data input and statistics are strictly operated in accordance with the requirements of the SPSS software to ensure the accuracy and practicality of the results. The data shows that 22%, 84%, 88% and 88% of the students think that they are required, like, adapt to the social requirements and improve their tennis skills, while 17%, 86%, 88% and 75% of the students in the control class. The results show that it is feasible to apply big data to college tennis teaching evaluation.

show abstract

Section: Introductionmentioning

confidence: 99%

University Tennis Teaching and Scientific Research Documents under the Background of Big Data

2021

IJECMR

View full text Add to dashboard Cite

show abstract

Controversial Past, Splendid Present, Unpredictable Future: A Brief Review of Alzheimer Disease History

Bermejo-Pareja,

del Ser

2024

JCM

View full text Add to dashboard Cite

Background: The concept of Alzheimer disease (AD)—since its histological discovery by Alzheimer to the present day—has undergone substantial modifications. Methods: We conducted a classical narrative review of this field with a bibliography selection (giving preference to Medline best match). Results: The following subjects are reviewed and discussed: Alzheimer’s discovery, Kraepelin’s creation of a new disease that was a rare condition until the 1970′s, the growing interest and investment in AD as a major killer in a society with a large elderly population in the second half of the 20th century, the consolidation of the AD clinicopathological model, and the modern AD nosology based on the dominant amyloid hypothesis among many others. In the 21st century, the development of AD biomarkers has supported a novel biological definition of AD, although the proposed therapies have failed to cure this disease. The incidence of dementia/AD has shown a decrease in affluent countries (possibly due to control of risk factors), and mixed dementia has been established as the most frequent etiology in the oldest old. Conclusions: The current concept of AD lacks unanimity. Many hypotheses attempt to explain its complex physiopathology entwined with aging, and the dominant amyloid cascade has yielded poor therapeutic results. The reduction in the incidence of dementia/AD appears promising but it should be confirmed in the future. A reevaluation of the AD concept is also necessary.

show abstract

Docosahexaenoic and Arachidonic Acids as Neuroprotective Nutrients throughout the Life Cycle

et al. 2021

View full text Add to dashboard Cite

The role of docosahexaenoic acid (DHA) and arachidonic acid (AA) in neurogenesis and brain development throughout the life cycle is fundamental. DHA and AA are long-chain polyunsaturated fatty acids (LCPUFA) vital for many human physiological processes, such as signaling pathways, gene expression, structure and function of membranes, among others. DHA and AA are deposited into the lipids of cell membranes that form the gray matter representing approximately 25% of the total content of brain fatty acids. Both fatty acids have effects on neuronal growth and differentiation through the modulation of the physical properties of neuronal membranes, signal transduction associated with G proteins, and gene expression. DHA and AA have a relevant role in neuroprotection against neurodegenerative pathologies such as Alzheimer’s disease and Parkinson’s disease, which are associated with characteristic pathological expressions as mitochondrial dysfunction, neuroinflammation, and oxidative stress. The present review analyzes the neuroprotective role of DHA and AA in the extreme stages of life, emphasizing the importance of these LCPUFA during the first year of life and in the developing/prevention of neurodegenerative diseases associated with aging.

show abstract

Evolution of the Research Literature and the Scientific Community of Alzheimer’s Disease from 1983-2017: A 35-Year Survey

Cited by 3 publications

References 131 publications

University Tennis Teaching and Scientific Research Documents under the Background of Big Data

University Tennis Teaching and Scientific Research Documents under the Background of Big Data

Controversial Past, Splendid Present, Unpredictable Future: A Brief Review of Alzheimer Disease History

Docosahexaenoic and Arachidonic Acids as Neuroprotective Nutrients throughout the Life Cycle

Contact Info

Product

Resources

About