Evolution of particle interactions between accidentally released aerosol particles generated from powdered engineered nanomaterials into a simulated workplace atmosphere

Kylafis, Georgios F.; Tomlin, Alison S.; Sleigh, Andrew; Vignes, Alexis

doi:10.1016/j.jaerosci.2018.12.008

Cited by 2 publications

(3 citation statements)

References 47 publications

(49 reference statements)

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“…Smaller particles have a large surface area per unit mass and can, therefore, occupy a larger surface area causing adverse health effects 39 . Furthermore, particles that deposit deeper into the respiratory system are difficult to remove, consequently causing adverse health effects due to interactions with tissues and cells 40 . Therefore, it is important to determine the uptake, redistribution, and clearance of particles in the human respiratory tract 41…”

Section: Introductionmentioning

confidence: 99%

“…39 Furthermore, particles that deposit deeper into the respiratory system are difficult to remove, consequently causing adverse health effects due to interactions with tissues and cells. 40 Therefore, it is important to determine the uptake, redistribution, and clearance of particles in the human respiratory tract. 41 Despite the risks associated with exposure to indoor PM 2.5 , indoor air quality is less researched relative to outdoor air quality-particularly in low-middle-income countries including the Republic of South Africa (RSA).…”

Section: Introductionmentioning

confidence: 99%

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Health risk assessment of particulate matter 2.5 in an academic metallurgy workshop

Mbazima

2022

Indoor Air

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Exposure to indoor PM 2.5 is associated with allergies, eye and skin irritation, lung cancer, and cardiopulmonary diseases. To control indoor PM 2.5 and protect the health of occupants, exposure and health studies are necessary. In this study, exposure to PM 2.5 released in an academic metallurgy workshop was assessed and a health risk assessment was conducted for male and female students and technicians.Polycarbonate membrane filters and an active pump operating at a flow rate of 2.5 L/ min were used to collect PM 2.5 from Monday to Friday for 3 months (August-October 2020) from 08:00-16:00. PM 2.5 mass concentrations were obtained gravimetrically, and the Multiple-Path Particle Dosimetry model was used to predict the deposition, retention, and clearance of PM 2.5 in the respiratory tract system. The risk of developing carcinogenic and non-carcinogenic effects among students and technicians was determined. The average PM 2.5 mass concentration for August was 32.6 μg/m 3 32.8 μg/m 3 for September, and 32.2 μg/m 3 for October. The head region accounted for the highest deposition fraction (49.02%), followed by the pulmonary (35.75%) and tracheobronchial regions (15.26%). Approximately 0.55 mg of PM 2.5 was still retained in the alveolar region 7 days after exposure. The HQ for male and female students was <1 while that of male and female technicians was >1, suggesting that technicians are at risk of developing non-carcinogenic health effects compared with students.The results showed a risk of developing carcinogenic health effects among male and female technicians (>1 × 10 −5 ); however, there was no excess cancer risk for students (<1 × 10 −6 ). This study highlights the importance of exposure and health studies in academic micro-environments such as metallurgy workshops which are often less researched, and exposure is underestimated. The results also indicated the need to implement control measures to protect the health of the occupants and ensure that the workshop rules are adhered to.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Health risk assessment of particulate matter 2.5 in an academic metallurgy workshop

Mbazima

2022

Indoor Air

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“…Nanoparticles in the ventilation chamber have attracted a lot of scientific attention with regard to their negative impacts on human health [6][7] . The distribution of nanoparticles in a ventilation chamber varies in time and space under the influence of turbulent transport and Brownian motion [8][9] . Kim et al [10] measured the turbulent and Brownian coagulation rates of polydisperse nanoparticles in a closed chamber at the atmospheric pressure, and showed that larger turbulent coefficients make the turbulent coagulation process become stronger.…”

Section: Introductionmentioning

confidence: 99%

Distribution of non-spherical nanoparticles in turbulent flow of ventilation chamber considering fluctuating particle number density

Shi

Lin

Yang

et al. 2021

Appl. Math. Mech.-Engl. Ed.

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The Reynolds-averaged general dynamic equation (RAGDE) for the nanoparticle size distribution function is derived, including the contribution to particle coagulation resulting from the fluctuating concentration. The equation together with that of a turbulent gas flow is solved numerically in the turbulent flow of a ventilation chamber with a jet on the wall based on the proposed model relating the fluctuating coagulation to the gradient of mean concentration. Some results are compared with the experimental data. The results show that the proposed model relating the fluctuating coagulation to the gradient of mean concentration is reasonable, and it is necessary to consider the contribution to coagulation resulting from the fluctuating concentration in such a flow. The changes of the particle number concentration M0 and the geometric mean diameter dg are more obvious in the core area of the jet, but less obvious in other areas. With the increase in the initial particle number concentration m00, the values of M0 and the standard deviation of the particle size σ decrease, but the value of dg increases. The decrease in the initial particle diameter leads to the reduction of M0 and σ, and the increase in dg. With the increase in the Reynolds number, particles have few chances of collision, and hence the coagulation rate is reduced, leading to the increase in M0 and σ, and the decrease in dg.

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Evolution of particle interactions between accidentally released aerosol particles generated from powdered engineered nanomaterials into a simulated workplace atmosphere

Abstract: This is a repository copy of Evolution of particle interactions between accidentally released aerosol particles generated from powdered engineered nanomaterials into a simulated workplace atmosphere.

Cited by 2 publications

References 47 publications

Health risk assessment of particulate matter 2.5 in an academic metallurgy workshop

Health risk assessment of particulate matter 2.5 in an academic metallurgy workshop

Distribution of non-spherical nanoparticles in turbulent flow of ventilation chamber considering fluctuating particle number density

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