Evolution of informed consent in research: From the Hippocratic Oath to the tailored consent
Jaime Fons-Martinez,
Carlos Murciano-Gamborino,
Javier Diez-Domingo
Abstract:Background Informed consent (IC) is essential in defending the autonomy of potential participants in clinical research. Despite the advances in research ethics, particularly in IC, the different guidelines and codes have not been fully implemented. Several studies have presented consent deficiencies that have resulted in unethical practices or poor understanding of the IC. Main body This article reviews the evolution of IC, from its philosophical origins and initial use in the Ottoman Empire (16th century) to … Show more
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