Evoked potential monitoring

Chansakul, Chakorn; Nair, Dileep

doi:10.1017/cbo9780511793851.009

Cited by 2 publications

(2 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This stimulation in sheep ( Danesh-Clough et al, 2001 ), pig ( Lenke et al, 1995 ), and humans ( Calancie et al, 1994 ) showed that the amplitude and latency of the EMG response in different muscles depend on the stimulated vertebra, again reflecting the rostrocaudal distribution of motoneuronal pools in the spinal cord. The EMG data presented previously ( Calancie et al, 1994 ; Chansakul and Nair, 2012 ) allow us to suppose that, with this type of stimulation, the M-wave may appear already in the near threshold current.…”

Section: Discussionmentioning

confidence: 67%

See 1 more Smart Citation

Mapping of the Spinal Sensorimotor Network by Transvertebral and Transcutaneous Spinal Cord Stimulation

Shkorbatova

Lyakhovetskii

Павлова

et al. 2020

Front. Syst. Neurosci.

View full text Add to dashboard Cite

Transcutaneous stimulation is a neuromodulation method that is efficiently used for recovery after spinal cord injury and other disorders that are accompanied by motor and sensory deficits. Multiple aspects of transcutaneous stimulation optimization still require testing in animal experiments including the use of pharmacological agents, spinal lesions, cell recording, etc. This need initially motivated us to develop a new approach of transvertebral spinal cord stimulation (SCS) and to test its feasibility in acute and chronic experiments on rats. The aims of the current work were to study the selectivity of muscle activation over the lower thoracic and lumbosacral spinal cord when the stimulating electrode was located intravertebrally and to compare its effectiveness to that of the clinically used transcutaneous stimulation. In decerebrated rats, electromyographic activity was recorded in the muscles of the back (m. longissimus dorsi), tail (m. abductor caudae dorsalis), and hindlimb (mm. iliacus, adductor magnus, vastus lateralis, semitendinosus, tibialis anterior, gastrocnemius medialis, soleus, and flexor hallucis longus) during SCS with an electrode placed alternately in one of the spinous processes of the VT12–VS1 vertebrae. The recruitment curves for motor and sensory components of the evoked potentials (separated from each other by means of double-pulse stimulation) were plotted for each muscle; their slopes characterized the effectiveness of the muscle activation. The electrophysiological mapping demonstrated that transvertebral SCS has specific effects to the rostrocaudally distributed sensorimotor network of the lower thoracic and lumbosacral cord, mainly by stimulation of the roots that carry the sensory and motor spinal pathways. These effects were compared in the same animals when mapping was performed by transcutaneous stimulation, and similar distribution of muscle activity and underlying neuroanatomical mechanisms were found. The experiments on chronic rats validated the feasibility of the proposed stimulation approach of transvertebral SCS for further studies.

show abstract

Section: Discussionmentioning

confidence: 67%

“…The latter allows an intraoperative monitoring of EMG activity of different muscle groups of human legs. This activity topically depends on the stimulation level ( Chansakul and Nair, 2012 ). Meanwhile, the screws may be used for neuromodulation in further treatment procedures ( Edidin, 2017 ).…”

Section: Discussionmentioning

confidence: 99%