Evidências sorológicas da circulação do arbovírus Rocio (Flaviviridae) na Bahia

Abstract

Recebido para publicação em 03/01/97. Brasileira de Medicina Tropical 30(6):511-515, nov-dez, 1997. Rocio (Flaviviridae) na Bahia. Revista da Sociedade Brasileira de Medicina Tropical 30:511-515, nov-dez, 1997. Revista da Sociedade COMUNICAÇÃO Comunicação. Straatmann A, Santos-Torres S, Vasconcelos PFC, Rosa APAT, Rodrigues SG, Tavares-Neto J. Evidências sorológicas da circulação do arbovírus

Arboviral diseases in the Western Brazilian Amazon: a perspective and analysis from a tertiary health & research center in Manaus, State of Amazonas

“…During this outbreak, more than 1,000 cases of encephalitis were reported; the case fatality ratio was 10%, and 30% of the survivors had neurologic sequelae. After this outbreak, serologic evidence of ROCV circulation in the Ribeira Valley, as well as in other parts of Brazil, has been reported, and public health authorities are concerned about a recurrence of ROCV outbreaks (23) (24) .…”

Molecular characterization of two rocio flavivirus strains isolated during the encephalitis epidemic in são paulo state, brazil and the development of a one-step rt-pcr assay for diagnosis

“…Likewise, ROCV may reappear causing catastrophic consequences the same way as WNV in the USA. The finding of antibodies to ROCV in eight patients, in the state of Bahia (1,200 Km from São Paulo) 20 years after the only ROCV epidemic, indicates that the virus was still circulating and that it had probably been carried by migratory birds 25 .…”

“…Viruses: Two strains of ROCV, SPAn37630, isolated on 02/28/ 1976 from a sentinel mouse exposed to the Cananéia County forest (25 o S, 48 o W), and SPH37623, obtained on 03/29/1976 from an autopsied human brain specimen were selected for molecular characterization. They were primarily isolated in suckling mice brain and their brain extracts were maintained lyophilized at -20 o C since then, for almost 30 years.…”

Persistence of experimental Rocio virus infection in the golden hamster (Mesocricetus auratus)

“…The epidemic lasted seven years and more than 1,000 cases of encephalitis were reported, including 100 deaths and more than 200 cases of severe central nervous system (CNS) sequelae (Iversson 1988, Iversson et al 1992. During the same period, five cases of encephalitis were reported in the northeastern region of the state of Paraná in areas bordering the affected region of SP (Straatmann et al 1997).…”

“…These two patients had chronic headaches. The three patients reported no travel outside of the city of Salvador during the six months prior to infection (Straatmann et al 1997).…”