Evidências moleculares da transmissão horizontal do vírus da hepatite C (VHC) entre cônjuges

Carvalho-Mello, Isabel Maria Vicente Guedes de

doi:10.11606/t.5.2006.tde-08012007-144312

Cited by 1 publication

(1 citation statement)

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“…A case-control study from Mexico however, did not support the association of GBS with chikungunya, though laboratory confirmation of chikungunya was rare in both cases and controls [51]. Since then, chikungunya is increasingly being reported as a common cause of CNS syndromes in children in coastal Kenya [52], adults in south-eastern Brazil [53], and individuals in Indonesia [54]. Diagnosis of chikungunya is by PCR or serological tests, primarily serum immunoglobulin M (IgM) antibodies, though some propose use of CSF IgM antibody detection for CNS disease [14].…”

Section: Chikungunyamentioning

confidence: 99%

Central nervous system infections in the tropics

Singh,

Rupali

2024

Current Opinion in Infectious Diseases

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Purpose of review Emerging and re-emerging central nervous system (CNS) infections are a major public health concern in the tropics. The reasons for this are myriad; climate change, rainfall, deforestation, increased vector density combined with poverty, poor sanitation and hygiene. This review focuses on pathogens, which have emerged and re-emerged, with the potential for significant morbidity and mortality. Recent findings In recent years, multiple acute encephalitis outbreaks have been caused Nipah, which carries a high case fatality. Arboviral infections, predominantly dengue, chikungunya and Zika are re-emerging increasingly especially in urban areas due to changing human habitats, vector behaviour and viral evolution. Scrub typhus, another vector borne disease caused by the bacterium Orientia tsutsugamushi, is being established as a leading cause of CNS infections in the tropics. Summary A syndromic and epidemiological approach to CNS infections in the tropics is essential to plan appropriate diagnostic tests and management. Rapid diagnostic tests facilitate early diagnosis and thus help prompt initiation and focusing of therapy to prevent adverse outcomes. Vector control, cautious urbanization and deforestation, and reducing disturbance of ecosystems can help prevent spread of vector-borne diseases. Regional diagnostic and treatment approaches and specific vaccines are required to avert morbidity and mortality.

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