Evidence to Practice: Botulinum Toxin in the Treatment of Spasticity Post Stroke

Teasell, Robert; Foley, Norine; Pereira, Shelialah; Sequeira, Keith; Miller, Thomas A.

doi:10.1310/tsr1902-115

Cited by 55 publications

(31 citation statements)

References 46 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…[551][552][553] Injection of botulinum toxin is used commonly to treat upper limb spasticity in patients with stroke and is recommended in several recent review articles and previously published guidelines as an important tool in the comprehensive management of poststroke spastic hypertonia. 149,[554][555][556][557] Injections of botulinum toxin A can reduce spasticity significantly as measured by the Ashworth scale. In a meta-analysis, botulinum toxin was shown to have a small but statistically significant effect on activity as measured by the Disability Assessment Scale after injection into the upper limb.…”

Section: Spasticitymentioning

confidence: 99%

Guidelines for Adult Stroke Rehabilitation and Recovery

Winstein¹,

Stein²,

Arena

et al. 2016

Stroke

2,078

953

View full text Add to dashboard Cite

e98Purpose-The aim of this guideline is to provide a synopsis of best clinical practices in the rehabilitative care of adults recovering from stroke. Methods-Writing group members were nominated by the committee chair on the basis of their previous work in relevant topic areas and were approved by the American Heart Association (AHA) Stroke Council's Scientific Statement Oversight Committee and the AHA's Manuscript Oversight Committee. The panel reviewed relevant articles on adults using computerized searches of the medical literature through 2014. The evidence is organized within the context of the AHA framework and is classified according to the joint AHA/American College of Cardiology and supplementary AHA methods of classifying the level of certainty and the class and level of evidence. The document underwent extensive AHA internal and external peer review, Stroke Council Leadership review, and Scientific Statements Oversight Committee review before consideration and approval by the AHA Science Advisory and Coordinating Committee. Results-Stroke rehabilitation requires a sustained and coordinated effort from a large team, including the patient and his or her goals, family and friends, other caregivers (eg, personal care attendants), physicians, nurses, physical and occupational therapists, speech-language pathologists, recreation therapists, psychologists, nutritionists, social workers, and others. Communication and coordination among these team members are paramount in maximizing the effectiveness

show abstract

Section: Spasticitymentioning

confidence: 99%

Guidelines for Adult Stroke Rehabilitation and Recovery

Winstein¹,

Stein²,

Arena

et al. 2016

Stroke

2,078

953

View full text Add to dashboard Cite

show abstract

“…Botulinum toxin injections are effective in managing adult spasticity in the upper limb and improving passive function [19]. However, botulinum toxin injections have been commonly used for focal upper limb spasticity [20], especially for the tone in the distal muscle groups; meanwhile, its effectiveness in improving active function has been quite controversial [21]. In our case, the patient accepted two years of systematic rehabilitation for his spastic right upper limb, including CMIT, bilateral arm training and botulinum toxin injections, but the effectiveness was still limited.…”

Section: Discussionmentioning

confidence: 99%

Cervical selective dorsal rhizotomy for treating spasticity in upper limb neurosurgical way to neurosurgical technique

Duan

Luo

Gao

et al. 2015

Interdisciplinary Neurosurgery

View full text Add to dashboard Cite

Selective dorsal rhizotomy is an effective method to reduce spasticity of the lower limbs. However, functional outcomes in the upper limb following selective dorsal rhizotomy at the cervical level have not been reported.Here we report the clinical course after selective dorsal rhizotomy at the cervical level in a patient with hemiplegic spasticity caused by brain injury. The selective dorsal rootlets at the cervical level were sectioned under electrophysiological monitoring. The patient was followed for 1 year to evaluate the outcome of surgery. The spasticity in the upper limb was reduced and the passive range of motion and function of movement improved. However, the effectiveness and the safety of operation should be studied further in clinical trials.

show abstract

“…В этой ситуации препаратом выбора является ботулинический токсин типа А (БТА), имеющий высокий уровень доказательности [18,19]. Результаты многочисленных исследований продемон-стрировали его безопасность и эффективность в лече-нии фокальной спастичности [20,21]. Локальное введение БТА позволяет решить много актуальных задач у больных: снизить мышечный тонус, улучшить положение конечности, изменить ее функциональные Нарушение позы и поло-жения конечностей.…”

Section: патофизиология спастичности нижней конечностиunclassified