Evidence that Streptobacillus moniliformis is an Intermediate Stage between a Corynebacterium and its L-form or Derived PPLO

Abstract

SUMMARYMorphological and serological evidence is presented to demonstrate that an organism morphologically identical with StreptobaciElus moniliformis is a stage intermediate to the L-form of a strain of Corynebacterium cervicis, that it is serologically closely related to a type culture of S . moniliformis, as well as to strains of MycopEasma hominis; thus supporting the conclusion that L l , derived from S. moniliformis, and M . hominis have a similar origin, and suggesting that S . moniliformis is an intermediate stage between a corynebacterium resembling C . cervicis and an L-form.

The Antigenic Structure of PPLO (Mycoplasma Hominis) and Related Bacteria

“…The distribution of shared antigens shown in Table 4 provides evidence that the corynebacterial variants which have been claimed to be derived from PPLO (Minck, 1953 Pease, 1962; H. E. Morton, personal communication) and the unrecorded examples quoted in this paper are, in fact, what they appear to be, since those examined in this study had several antigens in common, both with PPLO and other corynebacteria, and with members of the Haemophilus groups. And it is notable that the strains of bacteria most recently derived from PPLO (the oral derivatives in Table 4) possess the largest number of shared antigens.…”

“…Haemophilus may conceivably be a Gram-negative (or weakly Gram-positive) derivative of Corynebacterium, as Streptobacillus moniliformis has already proved to be (Pease, 1962). The relationship of Corynebacterium, Haemophilus and PPLO, as a degenerative series, was suggested by Pease & Bisset (1962).…”

The Antigenic Structure of Haemophilus and Corynebacterium Species from the Human Genital Tract Claimed to be Associated with or Derived from Mycoplasma Hominis

“…Several observations have been published tending to establish a relationship between Mycoplasma hominis and certain bacteria which have been described as species of the genus Corynebacterium (Minck, 1953 Pease, 1962) or of the genus Haemophilus (Amies & Jones, 1957). Whereas in most of these cases the mycoplasma (PPLO) concerned have been identified as M .…”

Dependency of Cell Size and Form of Proteus Mirabilis on the Peptone in the Culture Medium

“…The changes in Proteus bacilli described in this paper differ morphologically from those caused in Bacterium anitratum ex posed to various agents (1, 2) and in some other bacteria exposed to antibiotics (3,9). However, they conform with the changes de scribed in 3 B colonies which were induced in Proteus by peni cillin (5, 13).…”