1996
DOI: 10.1016/0034-5687(96)00063-1
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Evidence of nitric oxide in the exhaled gas of Asian elephants (Elephas maximus)

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Cited by 19 publications
(8 citation statements)
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“…NO is probably a phylogenetically old system, as it has been found in lower animals such as the blood-sucking bug Rhudius prulixus (24) and the crab Limulus polyphemus ( 2 3 , and still we have found considerable species differences in the upper airway NO concentration of higher animals (26). So far, nasal NO levels comparable to humans have only been reported from primates and elephants (20,26,27). There seems to be no obvious relation between the nasal NO levels and the extension of the sinus systems, which are poorly developed in premature and term infants and monkeys, but very extensive in, for instance, pigs and giraffes.…”
Section: Premature Infantsmentioning
confidence: 62%
See 1 more Smart Citation
“…NO is probably a phylogenetically old system, as it has been found in lower animals such as the blood-sucking bug Rhudius prulixus (24) and the crab Limulus polyphemus ( 2 3 , and still we have found considerable species differences in the upper airway NO concentration of higher animals (26). So far, nasal NO levels comparable to humans have only been reported from primates and elephants (20,26,27). There seems to be no obvious relation between the nasal NO levels and the extension of the sinus systems, which are poorly developed in premature and term infants and monkeys, but very extensive in, for instance, pigs and giraffes.…”
Section: Premature Infantsmentioning
confidence: 62%
“…The situation for NO is not likely to be equivalent to that of exhaled CO? (20), which is much less reactive and can be easily equilibrated between blood and alveolar gas. Consequently, expressing NO as concentrations may not be the ideal way to compare the magnitude of endogenous NO excretion in individuals of different sizes, ages or species, and in gases measured with different flow rate.…”
Section: Measurement Technique and No Excretion Ratementioning
confidence: 99%
“…Although no relationship has recently been found between size and exhaled NO measured in the trunk of Asian elephants [50], human data are rather more conflicting. No significant correlation has been reported between body weight or body surface and exhaled NO levels in either sex [51].…”
Section: Height Weight Age and Sexmentioning
confidence: 97%
“…Nitric oxide is produced endogenously within the respiratory tract and is detectable in exhaled gas of humans and other mammals (11,12). After the discovery that more than 80% of the total exhaled quantity is released into the upper airways (13,14), the epithelial cells in the paranasal sinuses were identified as the major source of NO release into the respiratory tract (15).…”
mentioning
confidence: 99%