Background The improper management of hazardous solid waste in dental care offices poses significant risks to public health and the environment. Dental offices generate hazardous waste, including biological and chemical contaminants, which can lead to infections, pollution, and harm if not managed properly. Effective waste management practices are crucial, yet compliance varies significantly across regions, especially in Latin America, due to limited resources, inadequate training, and insufficient infrastructure. This study compares hazardous waste management practices in dental offices in Talara, Peru, and Machala, Ecuador, to provide actionable recommendations for improvement. Policy and Implications In Peru, hazardous waste management involves critical steps such as conditioning, segregation, transport, storage, treatment, and disposal. Compliance minimizes exposure risks and environmental contamination. Ecuador emphasizes administrative and operational aspects, including policies, records, training, and procedures. Improving practices in both countries can model enhanced waste management across Latin America. Recommendations To address challenges in Talara and similar Latin American cities, it is essential to strengthen administrative systems, increase budget allocations for waste management, and develop comprehensive training programs. Waste management should be prioritized within public policy agendas with clear guidelines and accountability measures. Both cities need improved resource allocation, modern waste treatment facilities, and centralized storage solutions. Continuous education and certification programs are crucial. Implementing integrated policies, regular reviews, and robust compliance mechanisms based on Machala’s practices can benefit other regions. Public awareness campaigns and regional collaboration through workshops and research initiatives are also recommended. Conclusions Significant disparities in hazardous waste management exist between Talara and Machala. Talara requires strengthened systems and improved infrastructure, while Machala’s practices serve as a model. Tailored interventions can enhance public health and environmental outcomes across Latin America. Regular monitoring, evaluation, and collaboration are essential for sustained improvements.
