Evidence of cortical reorganization of language networks after stroke with subacute Broca's aphasia: a blood oxygenation level dependent-functional magnetic resonance imaging study

Qiu, Weihong; Wu, Huixiang; Qi, Yang; Kang, Zhuang; Chen, Zhaocong; Li, Kui; Qiu, Guo-rong; Xie, Chunqing; Wan, Guifang; Chen, Shaoqiong

doi:10.4103/1673-5374.198996

Cited by 15 publications

(12 citation statements)

References 44 publications

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“…Broca area covers not only the opercularis inferior frontal gyrus, but also the middle frontal and precentral gyrus. [ 21 ] The right middle and inferior frontal gyrus, precentral gyrus was really activated in our study. What's more, the right inferior frontal gyrus was crucial in the processing of emotional information and semantic integration.…”

Section: Discussionsupporting

confidence: 49%

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Exploring the neural correlates of self-related names in healthy subjects

Du²,

Chen³

et al. 2020

Medicine

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Objectives: This study aimed to clarify the neural correlates and underlying mechanisms of the subject's own name (SON) and the unique name derived from the SON (SDN). Methods: A name that was most familiar to the subject (SFN) was added as a self-related reference. We used 4 auditory stimuli—pure tone (1000 Hz), SON, SDN, and SFN—to evaluate the corresponding activated brain areas in 19 healthy subjects by using functional magnetic resonance imaging. Results: Our results demonstrated that pure tone activated the fewest brain regions. Although SFN was a very strong self-related stimulus, it failed to activate many midline structures. The brain regions activated by SON and SDN were very similar. SFN as a self-related stimulus was less self-related compared with SDN. What's more, the additionally activated fusiform gyrus and parahippocampal gyrus of SDN might revealed its processing path. Conclusions: SDN, which has created by us, is a new and self-related stimulus similar to SON. They might provide a useful reference for consciousness assessment with SON and SDN.

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Section: Discussionsupporting

confidence: 49%

“…[ 29 ] Qiu et al also found that when doing visual processing of an object, the occipital lobe and fusiform were engaged. [ 21 ] Therefore, the processing of SDN must involve the transformation from auditory to visual form at the fusiform gyrus. Because we had no actual auditory stimulus, the occipital lobe had no activation.…”

Section: Discussionmentioning

confidence: 99%

Exploring the neural correlates of self-related names in healthy subjects

Du²,

Chen³

et al. 2020

Medicine

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“…A neuroimaging study suggested the important role of the right inferior frontal gyrus for the recovery of language function patients with stroke with consequent aphasia; in fact, these findings demonstrated that, in the aphasic population, it could be observed a lower activation of the left brain areas and of the right inferior frontal. These results confirmed that language expression is associated with multiple brain areas [12]. To date, literature studies investigated the neural reorganizations in patients with conduction aphasia in terms of diagnosis and neuroimaging evidence [13][14][15][16].…”

Section: Introductionsupporting

confidence: 64%

Cortical Reorganization after Rehabilitation in a Patient with Conduction Aphasia Using High-Density EEG

et al. 2020

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Conduction aphasia is a language disorder occurred after a left-brain injury. It is characterized by fluent speech production, reading, writing and normal comprehension, while speech repetition is impaired. The aim of this study is to investigate the cortical responses, induced by language activities, in a sub-acute stroke patient affected by conduction aphasia before and after an intensive speech therapy training. The patient was examined by using High-Density Electroencephalogram (HD-EEG) examination, while was performing language tasks. The patient was she evaluated at baseline and after two months after rehabilitative treatment. Our results showed that an intensive rehabilitative process, in sub-acute stroke, could be useful for a good outcome of language deficits. HD-EEG results showed that left parieto-temporol-frontal areas were more activated after 2 months of rehabilitation training compared with baseline. Our results provided evidence that an intensive rehabilitation process could contribute to an inter- and intra-hemispheric reorganization.

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“…Similarly, study by Qiu et al . () suggests that the right inferior frontal gyrus is critical to aphasia recovery particularly in the subacute stage to increasing other brain areas critical to language performance. This emerging evidence suggests sex differences resulting in greater bilateral involvement during language tasks may be related to better aphasia outcomes which is traditionally related to the left hemisphere.…”

Section: Discussionmentioning

confidence: 99%

Gender differences in aphasia outcomes: evidence from the AphasiaBank

Sharma

Briley

Wright

et al. 2019

Intl J Lang & Comm Disor

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Background: Stroke is one of the leading causes of death in the United States. Aphasia is a language impairment which results as a consequence of stroke. Gender differences are reported in underlying mechanisms of stroke, however, gender differences in aphasia type and severity remain unclear. Aims: To examine gender differences in aphasia impairment based on data from AphasiaBank, a research repository of data obtained from studies of aphasia. Methods & Procedures:The data were collected from AphasiaBank for 294 persons with aphasia (PWA) (172 men, 122 women). Baseline comparisons by gender groups were completed using independent samples t-tests and Pearson Chi square statistics. Univariate comparisons of the total Western Aphasia Battery-Revised (WAB-R) -AQ and -R subtests' scores were compared between the two groups using independent samples t-tests. Multivariate comparisons were completed by using multivariate analysis of variance (MANOVA). Outcomes & Results: Gender differences were observed in the severity of aphasia with men exhibiting more severe aphasia than women. Analyses of WAB-R indicated greater impairment among men based on AQ and greater impairment was observed in individual subtest performance. Men exhibited statistically significantly lower WAB-R AQs than women (67.4 versus 75.6). Lower WAB-R AQs were derived from lower scores among men on individual subtests; information content, fluency, repetition, sentence completion, responsive speech and tests of comprehension (yes/no, auditory word recognition and sequential commands). Conclusions & Implications:This study offers evidence of gender differences in aphasia severity, global communication impairment and lower scores on individual subtests used to derive the WAB-R AQ. The limitations of the study with suggestions for future directions are presented.

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Evidence of cortical reorganization of language networks after stroke with subacute Broca's aphasia: a blood oxygenation level dependent-functional magnetic resonance imaging study

Cited by 15 publications

References 44 publications

Exploring the neural correlates of self-related names in healthy subjects

Exploring the neural correlates of self-related names in healthy subjects

Cortical Reorganization after Rehabilitation in a Patient with Conduction Aphasia Using High-Density EEG

Gender differences in aphasia outcomes: evidence from the AphasiaBank

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