Evidence of antifungal activity of wild rue (Peganum harmala L.) on phytopathogenic fungi

Bioefficacy of Some Aqueous Phytoextracts Against Clavibacter Michiganensis Subsp. Michiganensis (Smith), the Cause of Bacterial Canker of Tomato

“…These results suggest the presence of anti-microbial secondary metabolites in these plants. Our results are similar to those of Sarpeleh et al (2009) and Amel et al (2012). Sarpeleh et al (2009) chopped fresh P. harmela into small pieces and buried the plant material into bacteria-and fungi-infested soil two-three months prior to plantation.…”

“…Our results are similar to those of Sarpeleh et al (2009) and Amel et al (2012). Sarpeleh et al (2009) chopped fresh P. harmela into small pieces and buried the plant material into bacteria-and fungi-infested soil two-three months prior to plantation. They found that the buried plants or plant parts slowly released watersoluble anti-microbial substances which killed pathogens present in soil.…”

“…In our studies, the doses and amounts in soil amended with plant powder are most likely much lower than when pure substances are considered. Furthermore, there is no true contact between the pathogen in the plant and these substances in soil; unless some of them are directly absorbed by plant roots and go inside plant tissue to kill the pathogen as reported by Sarpeleh et al (2009). The possible activation of innate defense mechanism(s) of plants by natural elicitor compounds present in the dried powders of the medicinal plants (Walters et al 2005) is another major fascinating scenario responsible for the observed lower disease severity and enhancement of yield and yield-contributing factors of the treated plants.…”

Chemical fingerprint and simultaneous determination of alkaloids and flavonoids in aerial parts of genus Peganum indigenous to China based on HPLC‐UV: application of analysis on secondary metabolites accumulation

“…The whole plants of P. harmala have also been used as folk medicine in Turkey and Iran (Hemmateenejad et al, 2006;Kartal et al, 2003). Pharmacological studies on extracts and alkaloids separated from P. harmala have shown some biological activity and pharmacological effects, such as anti-tumor and analgesic effects Sobhani et al, 2002;Farouk (wileyonlinelibrary.com) DOI 10.1002/bmc.3218 et al, 2008, vasorelaxant activities (Astulla et al, 2008), antimicrobial and antifungal activities (Darabpour et al, 2011;Sarpeleh et al, 2009;Arshad et al, 2008), hypoglycemic effects (Singh et al, 2008), antidepressant effects (Farzin and Mansouri, 2006), hallucinogenic effects (Glennon et al, 2000), antileishmanial, insecticidal and repellent activities (Mohammad and Mazen, 2009) and promoting wound healing (Derakhshanfar et al, 2010), and were strong inhibitors of monoamine oxidase (Herraiz et al, 2010;Schwarz et al, 2003) and cholinesterase (Zheng et al, 2009(Zheng et al, , 2011Zhao et al, 2013). However, the seeds and aerial parts of P. nigellastrum and P. multisectum were sometimes used as substitutes of P. harmala in medicinal markets, which might result in inconsistencies in the clinical efficacy and therefore create a potential health hazard.…”

Phytochemical analysis of Ziziphus mucronata Willd. extract and screening for antifungal activity against peanut pathogens

“…A major challenge facing crop production is to provide tools for controlling field diseases that would also be able to maintain higher quality crop production (Sarpeleh et al, 2009). Disease management by chemical treatment has shown its limits by the development of resistances in many important pathogens and environmental pollution.…”