Evidence of alterations in transcallosal motor inhibition as a possible long-term consequence of concussions in sports: A transcranial magnetic stimulation study

Davidson, Travis; Tremblay, François

doi:10.1016/j.clinph.2016.07.012

Cited by 16 publications

(16 citation statements)

References 53 publications

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“…Behaviorally, changes have been demonstrated in reaching movements requiring complex visuomotor transformations [5], measurements of executive function and processing speed [9], tests of attention and concentration [38], and tasks probing verbal fluency function [34]. The functional alterations associated with a history of concussion may be related to corresponding changes occurring in brain structure and physiology [7,11,12,34,41,51]. It is important to note there is also an array of measurements across several functional domains that are not affected by a history of concussion.…”

Section: Introductionmentioning

confidence: 99%

A History of Concussion Does Not Lead to an Increase in Ocular Near Point of Convergence

et al. 2018

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Ocular near point of convergence (NPC) has been shown to be sensitive to the effects of concussion and subconcussive impacts. To determine if NPC is also sensitive to a previous history of concussion, male contact-sport athletes either with (n=26) or without (n=16) a history of at least one previous concussion had their NPC assessed. The results showed that participants with a history of concussion displayed NPC values (9.4±1.6 cm) indistinguishable from those with no history of concussion (8.4±2.1 cm, t-test, p=0.09). This was the case regardless of whether 1, 2, or 3 or more concussions had occurred and despite the fact participants with concussion (mean time since last concussion: 1136 days) suffered from an increased number and severity of symptoms as assessed with the SCAT 3 (3.6±2.2 vs. 2.13±1.89 symptoms, 6.1±4.1 vs. 3.19±2.99 severity, t-test, p<0.05). Taken together, these results imply that NPC may not be a suitable tool to assess the potential long-term effects of one or more concussions over a longer time frame.: Future research using larger sample sizes is warranted to evaluate the potential dose-response relationship between number of prior concussions and NPC.

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Section: Introductionmentioning

confidence: 99%

A History of Concussion Does Not Lead to an Increase in Ocular Near Point of Convergence

et al. 2018

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“…Thirteen studies presented long-term data, with group mean time post concussion ranging from 17 months [74] to 34.7 years [63]. MT data was presented in eight studies [24,58,63,64,[74][75][76][77] with only one study reporting significantly increased MT in both symptomatic and asymptomatic concussed groups, compared to control [56]. Three studies reported latency data, with no difference between groups [65,74,78].…”

Section: Long-term Tms Concussion Studiesmentioning

confidence: 99%

“…Intracortical inhibition was reported in all but one study [56]. Eleven studies presented cSP duration [24,[62][63][64][65][74][75][76][77][78][79][80]. Six studies reported significant lengthening of the cSP [24,62,63,[77][78][79], two studies reported significant shortening of the cSP [64,65], and three studies presented no change or mixed data [74,75,80].…”

Section: Long-term Tms Concussion Studiesmentioning

confidence: 99%

“…Eleven studies presented cSP duration [24,[62][63][64][65][74][75][76][77][78][79][80]. Six studies reported significant lengthening of the cSP [24,62,63,[77][78][79], two studies reported significant shortening of the cSP [64,65], and three studies presented no change or mixed data [74,75,80]. Eleven studies included paired-pulse inhibitory measures [24,[62][63][64][65][75][76][77][78][79][80].…”

Section: Long-term Tms Concussion Studiesmentioning

confidence: 99%

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Transcranial Magnetic Stimulation: A Tool for Quantifying Neurophysiological Changes in the Brain Following Concussion Injury in Sports

Pearce¹

2019

obm neurobiol

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Background: Sport-related concussion is a growing public health concern. Defined as a injury that disturbs neurological functions, concussion is characterised by a constellation of signs and symptoms. However, clinical imaging methods do not reveal any structural damage. Recently, neurophysiological techniques such as single and paired-pulse transcranial magnetic stimulation (TMS) are being applied to quantify neurophysiological changes (specifically corticospinal and intracortical excitation and intracortical inhibition) following concussion; both from an acute perspective, but also to investigate chronic changes associated with concussion injuries. The aim of this review paper is to present a systematic review and qualitative review on studies using TMS to assess concussion. Specifically, questions addressed refer to the efficacy of single and paired-pulse TMS on quantifying changes in neurophysiology following acute concussion and long-term changes in those with a history of repeated head trauma. Methods: Systematic searching of relevant databases for peer-reviewed literature between 1985 to present day. A qualitative synthesis of studies attaining the inclusion criteria was conducted.

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“…"Conceito" como avaliação da EC e "Contexto" como gravidade e tipos de TCE. Com relação à gravidade do TCE, onze estudos classificaram a condição clínica de sua amostra como TCE leve 77,79,80,83,84,85,89,91,93,95,96 , três como grave 81, 94,99 , dois como combinação de leve e moderado 92,100 , e apenas um como combinação de moderado e grave 82…”

Section: Método Da Revisão De Escopounclassified

Avaliação da excitabilidade cortical em pacientes com lesão axonial difusa tardia

Hayashi¹

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Aos pacientes vítimas de traumatismo cranioencefálico, que este estudo possa ajudar a Medicina no avanço de seu tratamento e cuidado. AGRADECIMENTOS Aos pacientes, juntamente com seus familiares, que nos permitiram estudar sua condição para buscarmos melhores tratamentos e cuidados na assistência ao Neurotrauma. Ao Prof Dr Wellingson Silva Paiva, meu orientador, que desde a Liga Acadêmica de Neurocirurgia incentivou meus estudos em Neurologia e acreditou em mim mesmo quando nem eu acreditava. Ao Prof Dr Ricardo Galhardoni por todos os ensinamentos, apoio, conselhos e valiosas contribuições na banca avaliadora do exame de qualificação deste projeto. Ao Prof Dr Daniel Ciampi de Andrade pelas valiosas contribuições na confecção do manuscrito para publicação deste estudo e também na banca avaliadora do exame de qualificação deste projeto. Ao Prof Dr André Russowsky Brunoni por permitir que este estudo fosse realizado no Serviço Interdisciplinar de Neuromodulação do Instituto de Psiquiatria do Hospital das Clínicas da Faculdade de Medicina da USP e pelas valiosas contribuições na banca avaliadora do exame de qualificação deste projeto. Ao Prof Dr Manoel Jacobsen Teixeira por permitir que este trabalho fosse desenvolvido no Departamento de Neurologia da Faculdade de Medicina da USP. A toda equipe do Serviço Interdisciplinar de Neuromodulação do Instituto de Psiquiatria do Hospital das Clínicas da Faculdade de Medicina da USP, pelo convívio e ensinamento durante o período em que este estudo foi desenvolvido. À enfermeira Rosa Rios pelo acolhimento caloroso no Serviço Interdisciplinar de Neuromodulação do Instituto de Psiquiatria do Hospital das Clínicas da Faculdade de Medicina da USP, além de todo apoio e ensinamento, paciência e ajuda com a logística de atendimento aos pacientes. À Sandra Falcon pela paciência e apoio logístico nos agendamentos dos pacientes. A todos os colegas do grupo de pesquisa em Neurotrauma pelas experiências, aprendizados, convívio e apoio.

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Evidence of alterations in transcallosal motor inhibition as a possible long-term consequence of concussions in sports: A transcranial magnetic stimulation study

Cited by 16 publications

References 53 publications

A History of Concussion Does Not Lead to an Increase in Ocular Near Point of Convergence

A History of Concussion Does Not Lead to an Increase in Ocular Near Point of Convergence

Transcranial Magnetic Stimulation: A Tool for Quantifying Neurophysiological Changes in the Brain Following Concussion Injury in Sports

Avaliação da excitabilidade cortical em pacientes com lesão axonial difusa tardia

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