Evidence for the Association between Chronotype and Lifelong Premature Ejaculation

Abstract

<b><i>Purpose:</i></b> This study aimed to investigate the relationships between intravaginal ejaculatory latency time (IELT), severity of disease, and chronotype in lifelong premature ejaculation (PE). <b><i>Materials and Methods:</i></b> Evaluation was made of 114 males with PE and 103 healthy individuals, and comparisons were made of self-estimated IELT, Arabic Index of Premature Ejaculation (AIPE), Pittsburg Sleep Quality Index (PSQI), and Morningness-Eveningness Questionnaire (MEQ). <b><i>Results:</i></b> The frequency of morningness chronotype (78.1%) was significantly higher, and Morningness-Eveningness Questionnaire (MEQ) scores were negatively correlated with both IELT (<i>r</i> = −0.490, <i>p</i> < 0.001) and Arabic Index of Premature Ejaculation (AIPE) scores (<i>r</i> = −0.639, <i>p</i> < 0.001) in the PE group. MEQ scores significantly predicted IELT (<i>t</i> = −2.465, <i>p</i> = 0.015) and AIPE scores (<i>t</i> = −4.003, <i>p</i> = 0.000) in the PE group but not in the control group. <b><i>Conclusion:</i></b> It can be asserted that morningness chronotype is more common, and ejaculatory latency time and PE severity are associated with chronotype in males with PE.

Erectile dysfunction, anxiety, perceived stress, and insomnia are more common among acquired premature ejaculation patients compared to other premature ejaculation syndromes

“…When examined according to chronotype, individuals with eveningness type have been shown to have worse sleep quality than individuals with morningness type, and their sexual understanding has tended to many partners and short relationships 41 . In a study examining whether there is a differences between LPE patients and normal healthy individuals in sleep chronotype, it was shown that LPE patients were more morningness type than the control group, and the increase in PE symptoms was negatively correlated with the scores obtained in the MEQ questionnaire 13 . However, there is no study in literature that has examined whether there is a difference between PE types in terms of chronotype.…”

“…41 In a study examining whether there is a differences between LPE patients and normal healthy individuals in sleep chronotype, it was shown that LPE patients were more morningness type than the control group, and the increase in PE symptoms was negatively correlated with the scores obtained in the MEQ questionnaire. 13 However, there is no study in literature that has examined whether there is a difference between PE types in terms of chronotype. The results obtained in the current study differ from the others in this aspect.…”

“…Most studies show an association between chronotype and mood and identify eveningness as a potential risk for depression 10 . There is only one study in the literature that has investigated whether there is a difference in sleep chronotype between healthy individuals and PE patients, and it was observed that the sleep chronotype has a decisive role in the development of PE 13 . However, to the best of our knowledge, there has been no previous study investigating this situation among the PE types.…”

Selective serotonin reuptake inhibitors combined with traditional Chinese medicine for premature ejaculation: A systematic review and meta‐analysis

“…These factors include the following categories: central neurotransmitter disorders, psychopsychological factors, penis paresthesia, endocrine factors, genetic factors, etc. 3,4 At present, the main clinical drugs for treating PE are selective serotonin reuptake inhibitors (SSRIs), topical anaesthetics, tricyclic antidepressants, phosphodiesterase 5 inhibitors (PDE5Is), α-receptor blockers, and other drugs. 5,6 The neural regulation of ejaculation is an extremely complex process that has not yet been fully elucidated.…”

“…Most experts believe that PE is the result of the joint action of biological factors and psychological factors. These factors include the following categories: central neurotransmitter disorders, psychopsychological factors, penis paresthesia, endocrine factors, genetic factors, etc 3,4 . At present, the main clinical drugs for treating PE are selective serotonin reuptake inhibitors (SSRIs), topical anaesthetics, tricyclic antidepressants, phosphodiesterase 5 inhibitors (PDE5Is), α‐receptor blockers, and other drugs 5,6…”