Evidence for the adaptive significance of circadian rhythms

Yerushalmi, Shai; Green, Rachel M.

doi:10.1111/j.1461-0248.2009.01343.x

Cited by 269 publications

(225 citation statements)

References 78 publications

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“…Evidence from multiple taxa supports a fitness advantage associated with the possession of an internal timekeeping mechanism, the circadian clock, that allows an organism to anticipate these changes to coordinate biological processes temporally with diel cycles (1,2). In plants, the fitness advantage of a clock that resonates with its environmental cycles has been attributed to the optimization of diurnal photosynthesis or nocturnal starch utilization (3,4), but it also is clear that the circadian clock controls many biological processes (5,6), and it seems likely that any fitness advantage associated with a functioning circadian clock accrues from multiple sources.…”

mentioning

confidence: 99%

Type II protein arginine methyltransferase 5 (PRMT5) is required for circadian period determination in Arabidopsis thaliana

Hong

Song

Lutz

et al. 2010

Proc. Natl. Acad. Sci. U.S.A.

117

118

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Posttranslational modification is an important element in circadian clock function from cyanobacteria through plants and mammals. For example, a number of key clock components are phosphorylated and thereby marked for subsequent ubiquitination and degradation. Through forward genetic analysis we demonstrate that protein arginine methyltransferase 5 (PRMT5; At4g31120) is a critical determinant of circadian period in Arabidopsis. PRMT5 is coregulated with a set of 1,253 genes that shows alterations in phase of expression in response to entrainment to thermocycles versus photocycles in constant temperature. PRMT5 encodes a type II protein arginine methyltransferase that catalyzes the symmetric dimethylation of arginine residues (Rsme2). Rsme2 modification has been observed in many taxa, and targets include histones, components of the transcription complex, and components of the spliceosome. Neither arginine methylation nor PRMT5 has been implicated previously in circadian clock function, but the period lengthening associated with mutational disruption of prmt5 indicates that Rsme2 is a decoration important for the Arabidopsis clock and possibly for clocks in general.circadian rhythms | circadian clock | luciferase

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mentioning

confidence: 99%

Type II protein arginine methyltransferase 5 (PRMT5) is required for circadian period determination in Arabidopsis thaliana

Hong

Song

Lutz

et al. 2010

Proc. Natl. Acad. Sci. U.S.A.

117

118

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“…The clock is a self-sustaining machinery that enables organisms to anticipate external fluctuations and in turn coordinate important physiological and developmental processes to occur at optimal times during the day, enhancing fitness (1,2). In Arabidopsis, the clock consists of a complex network of interlocked regulatory feedback loops between multiple components (3)(4)(5)(6).…”

mentioning

confidence: 99%

FBH1 affects warm temperature responses in the Arabidopsis circadian clock

Nagel

Pruneda‐Paz

Kay

2014

Proc. Natl. Acad. Sci. U.S.A.

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In Arabidopsis, the circadian clock allows the plant to coordinate daily external signals with internal processes, conferring enhanced fitness and growth vigor. Although external cues such as temperature can entrain the clock, an important feature of the clock is the ability to maintain a relatively constant period over a range of physiological temperatures; this ability is referred to as "temperature compensation." However, how temperature actually is perceived and integrated into the clock molecular circuitry remains largely unknown. In an effort to identify additional regulators of the circadian clock, including putative components that could modulate the clock response to changes in environmental signals, we identified in a previous large-scale screen a transcription factor that interacts with and regulates the promoter activity of a core clock gene. In this report, we characterized this transcription factor, FLOWERING BASIC HELIX-LOOP-HELIX 1 (FBH1) that binds in vivo to the promoter of the key clock gene CIRCADIAN CLOCK-ASSOCIATED 1 (CCA1) and regulates its expression. We found that upon temperature changes, overexpression of FBH1 alters the pace of CCA1 expression by causing a period shortening and thus preventing the clock from buffering against this change in temperature. Furthermore, as is consistent with the current mechanistic model of feedback loops observed in the clock regulatory network, we also determined that CCA1 binds in vivo to the FBH1 promoter and regulates its expression. Together these results establish a role for FBH1 as a transcriptional modulator of warm temperature signals and clock responses in Arabidopsis.T o adapt better to the daily and seasonal environmental changes, most organisms have an internal timekeeping mechanism known as the "circadian clock." The clock is a self-sustaining machinery that enables organisms to anticipate external fluctuations and in turn coordinate important physiological and developmental processes to occur at optimal times during the day, enhancing fitness (1, 2). In Arabidopsis, the clock consists of a complex network of interlocked regulatory feedback loops between multiple components (3-6). Synchronization of these components with external cues reinforces robust rhythms and allows the clock to coordinate efficiently the regulation of numerous biological outputs such as photosynthesis, photoperiodic flowering, hormone levels, and responses to biotic and abiotic stresses (1,3,(7)(8)(9). Key players in this interconnected network are the transcriptional components CIRCADIAN CLOCK-ASSOCIATED 1 (CCA1) and LATE ELONGATED HYPOCOTYL (LHY), two Myb-domain transcription factors, and TIMING OF CAB EXPRESSION 1 (TOC1). These three components, CCA1, LHY, and TOC1, form the core regulatory framework of the Arabidopsis circadian clock; their activity consists of transcriptional repression of each other and direct temporal regulation of most other clock components throughout the day (9-11).Integration and synchronization of environmental signals such as light and te...

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“…For all organisms, exact timing of behaviour to both daily and seasonal environmental cycles is crucial for survival and successful reproduction [1,2]. Consequently, the study of biological rhythms, chronobiology, is a vibrant and interdisciplinary research area in biology [3 -5].…”

Section: Introductionmentioning

confidence: 99%

Methods in field chronobiology

Dominoni

Åkesson

Klaassen

et al. 2017

Phil. Trans. R. Soc. B

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Chronobiological research has seen a continuous development of novel approaches and techniques to measure rhythmicity at different levels of biological organization from locomotor activity (e.g. migratory restlessness) to physiology (e.g. temperature and hormone rhythms, and relatively recently also in genes, proteins and metabolites). However, the methodological advancements in this field have been mostly and sometimes exclusively used only in indoor laboratory settings. In parallel, there has been an unprecedented and rapid improvement in our ability to track animals and their behaviour in the wild. However, while the spatial analysis of tracking data is widespread, its temporal aspect is largely unexplored. Here, we review the tools that are available or have potential to record rhythms in the wild animals with emphasis on currently overlooked approaches and monitoring systems. We then demonstrate, in three question-driven case studies, how the integration of traditional and newer approaches can help answer novel chronobiological questions in free-living animals. Finally, we highlight unresolved issues in field chronobiology that may benefit from technological development in the future. As most of the studies in the field are descriptive, the future challenge lies in applying the diverse technologies to experimental set-ups in the wild.

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Evidence for the adaptive significance of circadian rhythms

Cited by 269 publications

References 78 publications

Type II protein arginine methyltransferase 5 (PRMT5) is required for circadian period determination in Arabidopsis thaliana

Type II protein arginine methyltransferase 5 (PRMT5) is required for circadian period determination in Arabidopsis thaliana

FBH1 affects warm temperature responses in the Arabidopsis circadian clock

Methods in field chronobiology

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