Evidence for recent horizontal transfer of gypsy-homologous LTR-retrotransposon gtwin into Drosophila erecta followed by its amplification with multiple aberrations

Котнова, А. П.; Глухов, И. А.; Karpova, Nina N.; Salenko, V. B.; Lyubomirskaya, N. V.; Ilyin, Yu. V.

doi:10.1016/j.gene.2007.02.019

Cited by 13 publications

(11 citation statements)

References 20 publications

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“…References: 1, Mizrokhi and Mazo (1990); 2, Sánchez-Gracia et al (2005); 3, Kidwell (1983); 4, Brégliano and Kidwell (1983); 5, Bucheton et al (1984);6, Terzian et al (2000);7, Alberola and De Frutos (1996) Jordan and McDonald (1998);14, Jordan et al (1999); 15, Almeida and Carareto (2006);16, Ludwig and Loreto (2007); 17, Kotnova et al (2007);18, Fablet et al (2007);19, 20, 21, Hagemann et al (199219, 20, 21, Hagemann et al ( , 199619, 20, 21, Hagemann et al ( , 199822, 23, Haring et al (199522, 23, Haring et al ( , 2000; 24, García-Planells et al (1998);25, Clark and Kidwell (1997);26, 27, Daniels et al (198426, 27, Daniels et al ( , 1990b; 28 29, Clark et al (1994Clark et al ( , 1995; 30, Loreto et al (2001); 31, Silva and Kidwell (2000); 32, Castro and Carareto (2004); 33, Maruyama and Hartl (1991); 34, Lohe et al (1995); 35, Robertson and Lampe (1995);36, 37, Brunet et al (199436, 37, Brunet et al ( , 1999; 38, Arca and Savakis (2000); 39, Almeida and Carareto (2005) (Luan et al, 1993). The DNA transposons4LTR retrotransposons4non-LTR retrotransposons gradient observed in the Drosophilidae is consistent with the analysis carried out on a larger spectrum of species (Silva et al, 2004).…”

Section: Introductionmentioning

confidence: 99%

Revisiting horizontal transfer of transposable elements in Drosophila

2008

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Horizontal transfer (HT), defined as the transfer of genetic material between species, is considered to be an essential step in the 'life cycle' of transposable elements. We present a broad overview of suspected cases of HT of transposable elements in Drosophila. Hundred-one putative events of HT have been proposed in Drosophila for 21 different elements (5.0% refer to non-long terminal repeat (LTR) retrotransposons, 42.6% to LTR retrotransposons and 52.4% to DNA transposons). We discuss the methods used to infer HT, their limits and the putative vectors of transposable elements. We outline all the alternative hypotheses and ask how we can be almost certain that phylogenetic inconsistencies are due to HT.

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Section: Introductionmentioning

confidence: 99%

Revisiting horizontal transfer of transposable elements in Drosophila

2008

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“…The numbers of lines correspond to numbers of strains in Table 1 shown that the immunity to TE activity might be based on the mechanisms of RNA interference ). Its establishment includes three steps: the introduction of a new element to the cell (e.g., by means of horizontal transfer (Kotnova et al 2007); active transpositions of the intruder, its amplification and possible alteration; appearance of the element in some loci that play the role of TE activity regulators. The present paper is devoted to the study of retrotransposon gtwin in D. melanogaster G32 strain, which is characterized by active transpositions of the element in the past and its present stability.…”

Section: Discussionmentioning

confidence: 99%

“…The model explaining the formation of cellular immunity to TE activity suggests the following events: introduction of novel-to-the-host transposable element (Ludwig and Loreto 2007) followed by its active transpositions and alterations until it enters heterochromatic piRNA cluster resulting in its silencing by RNAi pathways Bergman et al 2006;Kotnova et al 2007;Salenko et al 2008).…”

Section: Introductionmentioning

confidence: 99%

Amplification of “defective” retrotransposon gtwin in D. melanogaster strain carrying large complex chromosomal aberration

et al. 2010

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Transposable elements (TE) are found in all eukaryotic genomes and play a significant role in their structure and functioning. The majority of mobile elements are silent in the genomes indicating the existence of cell control mechanisms of their activity. Establishment of immunity to TE is of great interest, but it cannot be studied directly and there are only few examples of present or recent active transpositions of mobile elements. G32, a Drosophila melanogaster strain, is characterized by the presence of large complex chromosomal aberration in the 3rd chromosome, active transpositions of gtwin in the past, and its stability at present. To address the question as to what had happened to the element while the cell took it under the control, we performed the detailed cytological and molecular analyses of gtwin's structure and its distribution in G32. Two variants of gtwin were found, one of which is amplified in G32 despite the alteration of tRNA-primer binding site. This element is accumulated in the aberrant chromosome and associated with the inversions breakpoints. Gtwin copies are predominantly localized in euchromatic regions and at least three of them are situated in heterochromatin. One copy was found in the piRNA cluster that might have caused silencing of the element.

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“…A hypothesis was proposed that this process could be managed by exploiting vectors including those of animal parasites, such as wasps and nematode worms, or microorganisms like fungi or bacteria or viruses themselves (Heath et al, 1999). We know that the gypsy/Ty3 class is the closest known group of retrotransposons to retroviruses (Springer and Britten, 1993), and several studies have provided evidence of the horizontal transfer of gypsy (Kotnova et al, 2007). Thus, Pifo_I should have the potential capacity of horizontal transfer in evolutionary history.…”

Section: The Organization Of 5ꞌutrsmentioning

confidence: 99%

Structural analysis of a 4414-bp element in Drosophila melanogaster

Yu¹,

Wang²,

Li³

et al. 2011

Genet. Mol. Res.

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ABSTRACT. We cloned a 4414-bp element from a mutant of Drosophila melanogaster. Its insertion site was 18,929,626 bp. Analysis of the nucleotide and amino acid sequences demonstrated that the element is homologous to Pifo_I, first obtained from D. yabuka, which belongs to the gypsy/Ty3 subfamily. We also obtained a 3754-bp length element from a wild-type fly by PCR, with a pair of primers designed from the conserved region of the 4414-bp length element. The two elements included a pair of long terminal repeats and part of the GAG and ENV proteins, but the POL protein was completely lost. This element is found in the subgenus of D. melanogaster, but it is a degenerate type of Pifo_I and is not infective. Also, a 714-bp region structured in 5.0 tandem repeats of 143 bp each was found in the 5ꞌUTR of the degenerate element; these could interact with transcription factor CF2. Phylogenetic analysis and alignment of amino acids indicated that the Pifo_I element was closer to the ZAM retrotransposon, which gave us some clues to their functional similarity. Based on these data, we propose that there is a relationship between the degenerate element

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Evidence for recent horizontal transfer of gypsy-homologous LTR-retrotransposon gtwin into Drosophila erecta followed by its amplification with multiple aberrations

Cited by 13 publications

References 20 publications

Revisiting horizontal transfer of transposable elements in Drosophila

Revisiting horizontal transfer of transposable elements in Drosophila

Amplification of “defective” retrotransposon gtwin in D. melanogaster strain carrying large complex chromosomal aberration

Structural analysis of a 4414-bp element in Drosophila melanogaster

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