Evidence for a New Avian Paramyxovirus Serotype 10 Detected in Rockhopper Penguins from the Falkland Islands

Miller, Patti J.; Afonso, Claudio L.; Spackman, Erica; Scott, Melissa A.; Pedersen, Janice C.; Senne, Dennis A.; Brown, Justin D.; Fuller, Chad M.; Uhart, Marcela; Karesh, William B.; Brown, Ian H.; Alexander, D. J.; Swayne, David E.

doi:10.1128/jvi.00822-10

Cited by 124 publications

(115 citation statements)

References 62 publications

Supporting

Mentioning

113

Contrasting

Unclassified

Order By: Relevance

“…ictvonline.org/virusTaxonomy.asp). Based on serological tests and complete genome sequence, APMVs have been officially classified into 12 serotypes designated as APMV-1 to 12 with NDV categorized into APMV-1 [7,10,65,106]. The virus genome has a negative-sense, non-segmented, single-stranded RNA with a genome length of approximately 15 [21,63].…”

Section: Newcastle Disease Virusmentioning

confidence: 99%

Newcastle disease in Nigeria: epizootiology and current knowledge of circulating genotypes

2016

View full text Add to dashboard Cite

Over the years, Newcastle disease (ND) has defied all available control measures. The disease has remained at the forefront of infectious diseases afflicting poultry production after avian influenza. Despite the continuous global use of million doses of ND vaccine annually, the causative pathogen, avian paramyxovirus type 1 also known as Newcastle disease virus (NDV) has continued to evolve causing, even more, a threat not only to the unvaccinated but the vaccinated flocks inclusive. The disease has been well studied in the developed countries where the virus is found in circulation. However, limited information exists on the epizootiology and circulating genotypes of the virus in developing countries where the majority of the flocks are raised on the extensive management system. Identification of virulent NDV in apparently healthy free-range ducks in this system calls for concern and pragmatic approach to investigate factor(s) that favour the virus inhabiting the ducks without clinical manifestation of the disease. Recently, novel genotypes (XIV, XVII, and XVIII) with peculiarity to West and Central African countries have been discovered and due to lack or poor surveillance system possibility of hitherto unreported genotypes are likely. This review elucidates and discusses available literature on the diversity of the circulating NDV genotypes across the West Africa countries and the epizootiology (molecular) of the disease in Nigeria with the view of identifying gaps in knowledge that can assist in the development of effective vaccines and control strategies to combat the peril of the disease.

show abstract

Section: Newcastle Disease Virusmentioning

confidence: 99%

Newcastle disease in Nigeria: epizootiology and current knowledge of circulating genotypes

2016

View full text Add to dashboard Cite

show abstract

“…APMVs belong to the genus Avulavirus of the subfamily Paramyxoviridae and are divided into nine serotypes, from APMV-1 to -9 [1]. Recently, viruses of three new serotypes, APMV-10, APMV-11 and APMV-12, were isolated from rockhopper penguins, common snipes and wigeons, respectively [2,10,17]. Subgrouping within the APMV serotype has also been Electronic supplementary material The online version of this article…”

mentioning

confidence: 99%

Characterization of a genetic and antigenic variant of avian paramyxovirus 6 isolated from a migratory wild bird, the red-necked stint (Calidris ruficollis)

et al. 2014

View full text Add to dashboard Cite

A hemagglutinating virus (8KS0813) was isolated from a red-necked stint. Hemagglutination inhibition and neutralization tests indicated that 8KS0813 was antigenically related to a prototype strain, APMV-6/duck/Hong Kong/18/199/77, but with an 8-and 16-fold difference, respectively, in their titers. The full genome sequence of 8KS0813 showed 98.6 % nucleotide sequence identity to that of APMV-6/duck/Italy/4524-2/07, which has been reported to belong to an APMV-6 subgroup, and showed less similarity to that of the prototype strain (70.6 % similarity). The growth of 8KS0813 and the prototype strain in four different cell cultures was greatly enhanced by adding trypsin. Interestingly, this virus induced syncytia only in Vero cells. 8KS0813 was identified as APMV-6/rednecked stint/Japan/8KS0813/08, but it is antigenically and genetically distinguishable from the prototype strain, suggesting that variant APMV-6 is circulating in migratory birds.Paramyxoviruses are pleomorphic enveloped viruses containing a non-segmented ssRNA genome that replicate in the cytoplasm of host cells. Members of a great variety of mammalian and avian species can be infected with these viruses [12]. Paramyxoviruses isolated from birds are divided into two distinct groups: avian paramyxovirus (APMV) and avian metapneumovirus. APMVs belong to the genus Avulavirus of the subfamily Paramyxoviridae and are divided into nine serotypes, from APMV-1 to -9 [1]. Recently, viruses of three new serotypes, APMV-10, APMV-11 and APMV-12, were isolated from rockhopper penguins, common snipes and wigeons, respectively [2,10,17]. Subgrouping within the APMV serotype has also been Electronic supplementary material The online version of this article

show abstract

“…APMVs are composed of the antigenically and genetically distinct avian paramyxovirus serotypes APMV 1 to 9 and two more APMV-10 and APMV-11 serotypes have been suggested (Miller et al, 2010;Briand et al, 2012). Based on antigenic and genetic characterization, proposed new APMV-12 group.…”

Section: Genome Characterization and Virus Diversitymentioning

confidence: 99%

Next generation sequencing technologies: Tool to study avian virus diversity

Kapgate¹,

Barbuddhe²,

Kumanan³

2015

View full text Add to dashboard Cite

Summary. -Increased globalisation, climatic changes and wildlife-livestock interface led to emergence of novel viral pathogens or zoonoses that have become serious concern to avian, animal and human health. High biodiversity and bird migration facilitate spread of the pathogen and provide reservoirs for emerging infectious diseases. Current classical diagnostic methods designed to be virus-specific or aim to be limited to group of viral agents, hinder identifying of novel viruses or viral variants. Recently developed approaches of next-generation sequencing (NGS) provide culture-independent methods that are useful for understanding viral diversity and discovery of novel virus, thereby enabling a better diagnosis and disease control. This review discusses the different possible steps of a NGS study utilizing sequence-independent amplification, high-throughput sequencing and bioinformatics approaches to identify novel avian viruses and their diversity. NGS lead to the identification of a wide range of new viruses such as picobirnavirus, picornavirus, orthoreovirus and avian gamma coronavirus associated with fulminating disease in guinea fowl and is also used in describing viral diversity among avian species. The review also briefly discusses areas of viral-host interaction and disease associated causalities with newly identified avian viruses.

show abstract

Evidence for a New Avian Paramyxovirus Serotype 10 Detected in Rockhopper Penguins from the Falkland Islands

Cited by 124 publications

References 62 publications

Newcastle disease in Nigeria: epizootiology and current knowledge of circulating genotypes

Newcastle disease in Nigeria: epizootiology and current knowledge of circulating genotypes

Characterization of a genetic and antigenic variant of avian paramyxovirus 6 isolated from a migratory wild bird, the red-necked stint (Calidris ruficollis)

Next generation sequencing technologies: Tool to study avian virus diversity

Contact Info

Product

Resources

About