Evidence for a connection between COVID-19 and exposure to radiofrequency radiation from wireless communications including 5G

Rubik, Beverly; Brown, R. R.

doi:10.31219/osf.io/9p8qu

“…328,329 More recently, a few specific papers focused on the possible role of peculiar types of EMF in SARS-CoV-2 pathogenicity, 330,331 and a recent publication has presented some data about the detrimental interaction of radiofrequencies specifically with VGCC and with cation metabolism, erythrocytes, hemoglobin, coagulation, immune system and oxidative stress. 332 In view of the role of both the cell membrane electro-chemical changes and the cations in COVID-19, some more research could be performed to assess any possible inter-relationship of polluting environmental factors with VGCC, cellular membrane and cytoplasm ionic changes.…”

Section: G) Hemoglobin Hemementioning

confidence: 99%

COVID-19, Cation Dysmetabolism, Sialic Acid, CD147, ACE2, Viroporins, Hepcidin and Ferroptosis: A Possible Unifying Hypothesis

Cavezzi

¹

,

Menicagli

²

,

Troiani³

et al. 2022

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Background: iron and calcium dysmetabolism, with hyperferritinemia, hypoferremia, hypocalcemia and anemia have been documented in the majority of COVID-19 patients at later/worse stages. Furthermore, complementary to ACE2, both sialic acid (SA) molecules and CD147 proved relevant host receptors for SARS-CoV-2 entry, which explains the viral attack to multiple types of cells, including erythrocytes, endothelium and neural tissue. Several authors advocated that cell ferroptosis may be the core and final cell degenerative mechanism. Methods: a literature research was performed in several scientific search engines, such as PubMed Central, Cochrane Library, Chemical Abstract Service. More than 500 articles were retrieved until mid-December 2021, to highlight the available evidence about the investigated issues. Results: based on COVID-19 literature data, we have highlighted a few pathophysiological mechanisms, associated with virus-based cation dysmetabolism, multi-organ attack, mitochondria degeneration and ferroptosis. Our suggested elucidated pathological sequence is: a) spike protein subunit S1 docking with sialylated membrane glycoproteins/receptors (ACE2, CD147), and S2 subunit fusion with the lipid layer; b) cell membrane morpho-functional changes due to the consequent electro-chemical variations and viroporin action, which induce an altered ion channel function and intracellular cation accumulation; c) additional intracellular iron concentration due to a deregulated hepcidin-ferroportin axis, with higher hepcidin levels. Viral invasion may also affect erythrocytes/erythroid precursors, endothelial cells and macrophages, through SA and CD147 receptors, with relative hemoglobin and iron/calcium dysmetabolism. AB0 blood group, hemochromatosis, or environmental elements may represent possible factors which affect individual susceptibility to COVID-19. Conclusions: our literature analysis confirms the combined role of SA molecules, ACE2, CD147, viroporins and hepcidin in determining the cation dysmetabolism and final ferroptosis in the cells infected by SARS-CoV-2. The altered ion channels and electrochemical gradients of the cell membrane have a pivotal role in the virus entry and cell dysmetabolism, with subsequent multi-organ immune-inflammatory degeneration and erythrocyte/hemoglobin alterations.

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“…326,327 More recently, a few specific papers focused on the possible role of peculiar types of EMF in SARS-CoV-2 pathogenicity, 328,329 and a recent publication has presented some data about the detrimental interaction of radiofrequencies specifically with VGCC and with cation metabolism, erythrocytes, hemoglobin, coagulation, immune system and oxidative stress. 330 In view of the role of both the cell membrane electro-chemical changes and the cations in COVID-19, some more research could be performed to assess any possible inter-relationship of polluting environmental factors with VGCC, cellular membrane and cytoplasm ionic changes.…”

Section: G) Hemoglobin Hemementioning

confidence: 99%

COVID-19, Cation Dysmetabolism, Sialic Acid, CD147, ACE2, Viroporins, Hepcidin and Ferroptosis: A Possible Unifying Hypothesis

Cavezzi

¹

,

Menicagli

²

,

Troiani

³

et al. 2022

View full text Add to dashboard Cite

Background: iron and calcium dysmetabolism, with hyperferritinemia, hypoferremia, hypocalcemia and anemia have been documented in the majority of COVID-19 patients at later/worse stages. Furthermore, complementary to ACE2, both sialic acid (SA) molecules and CD147 proved relevant host receptors for SARS-CoV-2 entry, which explains the viral attack to multiple types of cells, including erythrocytes, endothelium and neural tissue. Several authors advocated that cell ferroptosis may be the core and final cell degenerative mechanism. Methods: a literature research was performed in several scientific search engines, such as PubMed Central, Cochrane Library, Chemical Abstract Service. More than 500 articles were retrieved until mid-December 2021, to highlight the available evidence about the investigated issues. Results: based on COVID-19 literature data, we have highlighted a few pathophysiological mechanisms, associated with virus-based cation dysmetabolism, multi-organ attack, mitochondria degeneration and ferroptosis. Our suggested elucidated pathological sequence is: a) spike protein subunit S1 docking with sialylated membrane glycoproteins/receptors (ACE2, CD147), and S2 subunit fusion with the lipid layer; b) cell membrane morpho-functional changes due to the consequent electro-chemical variations and viroporin action, which induce an altered ion channel function and intracellular cation accumulation; c) additional intracellular iron concentration due to a deregulated hepcidin-ferroportin axis, with higher hepcidin levels. Viral invasion may also affect erythrocytes/erythroid precursors, endothelial cells and macrophages, through SA and CD147 receptors, with relative hemoglobin and iron/calcium dysmetabolism. AB0 blood group, hemochromatosis, or environmental elements may represent possible factors which affect individual susceptibility to COVID-19. Conclusions: our literature analysis confirms the combined role of SA molecules, ACE2, CD147, viroporins and hepcidin in determining the cation dysmetabolism and final ferroptosis in the cells infected by SARS-CoV-2. The altered ion channels and electrochemical gradients of the cell membrane have a pivotal role in the virus entry and cell dysmetabolism, with subsequent multi-organ immune-inflammatory degeneration and erythrocyte/hemoglobin alterations.

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“…This technology leads to many doubts and concerns about the future of man; it is in fact able to interact with the connected devices and in a fraction of a second can process data and intervene on the devices. This leads to possible serious limitations of human freedom, as we have known it until the end of 2019 [29,30]. These mRNA sera appear to do profound and extensive immune suppression.…”

Section: A Very Dubious Current Use Of Nanotechnology: the Gene Seramentioning

confidence: 99%

Post-Trans Human Techno Science as Help or Threat: An Overview with Emphasis on a Current Nanotechnology Application

Sia¹

2022

EOIJ

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Aim: The paper focuses on the progressive growth of a particular direction of science which, in the name of an alleged human and social progress, is imposing itself in a disputable way, progressively stifling people’s freedom of choice. Never as in this time, technoscience has been trying to impose its highly questionable rules, to the detriment of human freedom and health. True science is currently often confused with a sort of scientism. The scientific medicine fights against unofficial medicines and is enjoying a credit comparable to a religion. Methods: The paper analyzes the role of technoscience in the post-transhuman framework, with particular attention to nanotechnologies and to the unfortunate consequences emerging from its recent application in the field of gene sera in relation to Covid-19 pandemic. Results: Technoscience and nanotechnological applications, closely related to it, can become dangerous tools for the future of humanity if their use is not properly controlled through truly scientific methods. An illuminating example of this is the use of experimental drugs, improperly called vaccines, from the past year throughout the world. Conclusion: We cannot speak of true science and technoscience at the service of the individual if freedom and human dignity are not respected or overshadowed through social impositions without real scientific basis. Scientific discoveries and technological inventions are acceptable if they respect human dignity and aim at the common good and not at the advantage of an elite.

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Evidence for a connection between COVID-19 and exposure to radiofrequency radiation from wireless communications including 5G

Cited by 15 publications

References 73 publications

COVID-19, Cation Dysmetabolism, Sialic Acid, CD147, ACE2, Viroporins, Hepcidin and Ferroptosis: A Possible Unifying Hypothesis

COVID-19, Cation Dysmetabolism, Sialic Acid, CD147, ACE2, Viroporins, Hepcidin and Ferroptosis: A Possible Unifying Hypothesis

COVID-19, Cation Dysmetabolism, Sialic Acid, CD147, ACE2, Viroporins, Hepcidin and Ferroptosis: A Possible Unifying Hypothesis

Post-Trans Human Techno Science as Help or Threat: An Overview with Emphasis on a Current Nanotechnology Application

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