Evidence based radiation oncology with existing technology

Isa, N.

doi:10.1016/j.rpor.2013.09.002

Cited by 15 publications

(8 citation statements)

References 73 publications

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“…Currently, many new therapeutic options and diagnostic tools are available in current OC oncology [21][22][23][24]. For OC staging evaluation, we can also use a new technology that uses invisible light.…”

Section: Preoperative Assessmentmentioning

confidence: 99%

Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for treatment of ovarian cancer

Połom¹,

Roviello

Generali

et al. 2016

International Journal of Hyperthermia

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Hyperthermic intraperitoneal chemotherapy (HIPEC), a strategy combining maximal cytoreductive surgery and maximal regional chemotherapy, has been applied to treat ovarian cancer resulting in long-term survival rates in selected patients. However, the status of HIPEC in ovarian cancer remains an experimental procedure, given the many variables among the data and trials reviewed, to enable us to derive strong conclusions about its role from this overview. In this review we discuss treatment with HIPEC in patients with ovarian cancer and future prospective of its use in clinical setting. HIPEC is an effective tool in the treatment of selected patients with peritoneal carcinomatosis from ovarian cancer. Unfortunately, due to the lack of randomised trials, the evidence of HIPEC is very limited. Future randomised studies are awaited to define the role and clinical impact of HIPEC in ovarian cancer.

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Section: Preoperative Assessmentmentioning

confidence: 99%

Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for treatment of ovarian cancer

Połom¹,

Roviello

Generali

et al. 2016

International Journal of Hyperthermia

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“…for patients with tumours affected by respiratory motion. Along with these developments, the optimal use of available techniques still poses a challenge to the irradiation of non-small cell lung cancer (NSCLC) patients [1][2][3]. Of course, the most important concern is the intra-fraction motion due to breathing.…”

Section: Introductionmentioning

confidence: 99%

Modelling the effects of lung cancer motion due to respiration

Adamczyk

Adamczyk²,

Piotrowski

2018

Nukleonika

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Background and objectives: To justify the concept of validating conformal versus intensity-modulated approach in the treatment of non-small cell lung cancer (NSCLC). Materials and methods: For 10 patients representative of the spectrum of tumour sizes and locations, two plans were prepared: one with three-dimensional conformal radiation therapy (3DCRT) technique and the other with intensity-modulated radiation therapy (IMRT) technique. Preliminary measurements were performed in static conditions. For each of the field angles considered, the motion kernel was generated to simulate tumour motion trajectories, with the largest amplitude in the cranio-caudal direction of 4, 6, and 8 mm. The measurement results determined the agreement between the planned and measured doses. Results: No statistically significant differences were found between the motion patterns, with the smallest amplitudes for clinical target volume in 3DCRT. For IMRT, the significant differences between 0 mm vs. 6 mm and 0 mm vs. 8 mm amplitudes were found. The motion impact on delivered vs. planned doses had less effect on the oesophagus in 3DCRT compared to that in IMRT. The observed differences were comparable for the heart. Interpretation and conclusions: For maximal amplitudes below 4 mm, the disagreement between planned and delivered doses can be neglected. However, the amplitudes above 5 mm and 7 mm lead to significant changes in IMRT and 3DCRT dose distribution, respectively.

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“…Theoretically, the solution of dilemma is to de ionizing irradiation beam to tumor cells as targeting. Therefore, conformal three-dimensional and intensity modulated radio therapy are used in order to provide closer conformation of irradiation fields to tumor region to decrease ionizing irradiation of healthy cells as non (Han et al, 2016), (Isa, 2013) and (Zabihzadeh Despite these advances in conformal radio therapy, treatment with irradiation is still to remain cause of morbidity among patients with cancer. It can be leaded to limit the delivery of curative irradiation doses to tumor cells.…”

Section: Introductionmentioning

confidence: 99%

“…dimensional and intensity modulated radio therapy are used in order to provide closer conformation of irradiation fields to tumor region to decrease ation of healthy cells as non-targeting tissues (Isa, 2013) and (Zabihzadeh et al, 2016). Despite these advances in conformal radio therapy, treatment with irradiation is still to remain cause of morbidity among t can be leaded to limit the delivery of curative irradiation doses to tumor cells.…”

Section: Introductionmentioning

confidence: 99%

The radiosensitizer effect of 2,6-bis-(2,6 dichlorobenzylidene) cyclohexanone as a selective thiol alkylator on ht29 cell line

Doroudi¹,

KoroushZarei²,

Mohammadi³

et al. 2017

Int j curr adv res

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Evidence based radiation oncology with existing technology

Abstract: In light of the changes in technology, the ever-increasing access of developing countries to such technology, and its current coverage in Latin America, any efforts in this area should be aimed at improving the quality of the radiotherapy departments and centers that are already in place.

Cited by 15 publications

References 73 publications

Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for treatment of ovarian cancer

Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for treatment of ovarian cancer

Modelling the effects of lung cancer motion due to respiration

The radiosensitizer effect of 2,6-bis-(2,6 dichlorobenzylidene) cyclohexanone as a selective thiol alkylator on ht29 cell line

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