Evidence-Based Medicine

Vasconcellos, Adam; Shin, Jennifer J.

doi:10.1007/978-3-319-26794-4_1

Cited by 1 publication

(2 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…If in the case of PHPT parathyroidectomy is the gold standard of treatment and in most cases leads to complete cure of patients, in the case of SHPT on the background of CKD -is only one stage of multicomponent therapy helps to improve biochemical parameters and positively affect the bone system. [4,25].…”

Section: Discussionmentioning

confidence: 99%

“…In accordance with recommendations of KDIGO2017 a parathyroidectomy is recommended to the patients with SHPT regardless of the stage of process at presence of resistance to medicine therapy [3]. The aim of treatment of SHPT is normalization of mineral metabolism, prophylaxis of diseases of bones and prevention of extra-skeletal disease [4,5].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Laboratory criteria for the persistence of secondary hyperparathyroidism in patients with chronic kidney disease

Urina¹,

Palamarchuk²,

Товкай³

et al. 2020

J Educ Health Sport

View full text Add to dashboard Cite

Secondary hyperparathyroidism is a complication of chronic kidney disease in both the non-dialysis and dialysis stages. Even modern advances in drug therapy cannot change the fact that most CKD patients require surgical treatment. The purpose of the treatment of SHPT is to normalize mineral metabolism, prevent bone diseases and prevent extraosseous manifestations. One of the methods of surgical treatment is subtotal parathyroidectomy.Persistence or recurrence of the disease occurs in 5-30% of cases.Purpose of the study. To determine laboratory criteria for the persistence of SHPT in patients with chronic kidney disease on the second day after parathyroidectomy. Materials and methods.The study involved 118 patients with end-stage CKD with prolonged renal replacement therapy. All patients had clinical and laboratory signs of secondary hyperparathyroidism. In the period from 2009 to 2019, patients underwent subtotal parathyroidectomy. The patients were divided into two groups. This division was based on the presence of persistence or recurrence of the disease. The main group included 20 patients with Conclusions. Using the subtotal parathyroidectomy in our study, the persistent of SHPT occurred in 16.9% of cases. A decrease in PTH levels on the second day after surgery less than 76% comparatively to the preoperative level should be considered as a predictor of the development of disease persistence. A reduction in PTH of more than 90.9% may be an indication of sustained remission.

show abstract

Section: Discussionmentioning

confidence: 99%