Evidence‐based guideline for the prevention and management of perioperative infection

Abstract

Background:We have updated the guideline for preventing and managing perioperative infection in China, given the global issues with antimicrobial resistance and the need to optimize antimicrobial usage and improve hospital infection control levels. Methods:We conducted a comprehensive evaluation of the evidence for prevention and management of perioperative infection, based on the concepts of the Grading of Recommendations Assessment, Development and Evaluation (GRADE) system. The strength of recommendations was graded and voted using the Delphi method and the nominal group technique. Revisions were made to the guidelines in response to feedback from the experts.Results: There were 17 questions prepared, for which 37 recommendations were made. According to the GRADE system, we evaluated the body of evidence for each 52 WANG ET AL. clinical question. Based on the meta-analysis results, recommendations were graded using the Delphi method to generate useful information. Conclusions:This guideline provides evidence to perioperative antimicrobial prophylaxis that increased the rational use of prophylactic antimicrobial use, with substantial improvement in the risk-benefit trade-off.

Robotic-assisted laparoscopic radical hysterectomy for early-stage cervical cancer: The more experienced the bedside assistant, the better?

“…While in our study, even in the BA 1 group, the average time was 204 min, and only 4 cases were more than 240 min, Therefore, we speculate that the prolonged operative time caused by the deficient experience of BA is not enough for increasing the occurrence of postoperative adverse events. Next, According to the guideling of the prevention and management of perioperative infection, during RALH, supplementary antibiotics were administered 3 h after the initial antibiotic dose has been given [ 32 ]. This measure may effectively control the occurrence of postoperative infections.…”

Cefoxitin versus Cefepime for the Prevention of Perioperative Infection in Elderly Patients Undergoing Colorectal Cancer Surgery: A Retrospective Study

“…Postoperative infections, especially surgical site infections (SSIs), have been associated with increased mortality rates, elevated hospitalization costs, and extended hospital stays. Colorectal surgery is among the procedures with the highest SSI incidence rates, potentially reaching up to 9.5%, even when adhering to antimicrobial prophylaxis guidelines [1][2][3]. Beyond SSIs, other postoperative infections such as intra-abdominal infections (IAIs), hospital-acquired pneumonia (HAP), and urinary tract infection (UTI) also signi cantly contributed to hospital readmissions, costs, and mortality [4].…”