Evidence based Ayurveda Practice

P, Ashok Kumar

doi:10.4172/2167-1206.1000e108

Cited by 3 publications

(1 citation statement)

References 8 publications

(7 reference statements)

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“…The practice of evidence-based medicine requires integrating individual clinical experience with the best available external clinical evidence [9] . The four main aspects of deciding treatment in Ayurveda include “tradition (inherited from ancestors), conventional (from other examples), belief (with the formula of dravya, guna, virya and karma)” and EBM, a combination of all these parameters to personalize the treatment [10] . The complexities involved in carrying out trials in Ayurveda are well-known such as treatment plan based on prakriti ; difficulty in using blinding technique due to the odor and taste of Ayurveda medicine; holistic approach such as modification of behavior and dietary regimes associated with Ayurveda treatment and the differential assessment of outcomes based on doshas; lack of standardization of Ayurveda medicines and variation in the method and mode of drug administration [11] .…”

Section: Discussionmentioning

confidence: 99%

Clinical trials in Ayurveda: Analysis of clinical trial registry of India

Sridharan

Sivaramakrishnan

2016

Journal of Ayurveda and Integrative Medicine

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Ayurveda is one of the complementary and alternative systems of medicine requiring generation of high quality evidence for rational practice. Evidence can be generated from study designs and the present study is an attempt to critically assess the registered studies in the field of Ayurveda from clinical trial registry of India. We found low number of trials conducted with more focus required on the quality of these studies to contribute to high quality evidence.

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Section: Discussionmentioning

confidence: 99%

Clinical trials in Ayurveda: Analysis of clinical trial registry of India

Sridharan

Sivaramakrishnan

2016

Journal of Ayurveda and Integrative Medicine

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Assessment of membrane stability, central nervous system depressant, and gut motility effects of Lablab purpureus seeds

Roy

Bhowmik

Uddin

et al. 2022

J Herbmed Pharmacol

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Introduction: Lablab purpureus, under the family of Fabaceae, is a plant with various pharmacological activities. The present study was aimed to investigate the phytoconstituents, membrane stabilizing activity, central nervous system (CNS) depressant potential, and gastrointestinal (GI) motility of the methanol extract of L. purpureus seeds (MELPS).Methods: The methanol plant extract was screened for different phytochemical groups. Mice were classified into four groups for in vivo activities. Group-I was designated as negative control and received distilled water (10 mL/kg body weight); group-II served as positive control and received diazepam (1 mg/kg body weight). Group-III and group-IV both were experimental groups and received plant extract at 200 and 400 mg/kg body weight, respectively.Results: Alkaloids, carbohydrates, saponins, glycosides, tannins, phenols, flavonoids, and proteins were found after phytochemical analysis. On hypotonic solution-induced hemolysis of erythrocyte membrane, MELPS9 (9 mg/mL) resulted in the highest percentage of inhibition (60.51 ± 0.889), and on heat-induced hemolysis, MELPS9 (9 mg/mL) resulted in the highest percentage of inhibition (33.97 ± 0.21). In the case of the CNS depressant potential experiment, mice that received a sample at a dose of 400 mg/kg body weight showed the highest result (54.40 ± 4.51) compared with the positive control (14.2 ± 3.70) (P < 0.001). Similarly, 400 mg/kg dose sample exhibited the highest percentage of inhibition (60.51 ± 0.889) of hemolysis and GI motility (22.26%).Conclusion: It can be concluded that the MELPS has potential membrane stability, CNS depressant, and antimotility effects.

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Ayurveda Medication Non Adherence: Implications for Clinical Practice and Research

Panda¹

2016

J Tradi Med Clin Natur

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Evidence based Ayurveda Practice

Cited by 3 publications

References 8 publications

Clinical trials in Ayurveda: Analysis of clinical trial registry of India

Clinical trials in Ayurveda: Analysis of clinical trial registry of India

Assessment of membrane stability, central nervous system depressant, and gut motility effects of Lablab purpureus seeds

Ayurveda Medication Non Adherence: Implications for Clinical Practice and Research

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