2021
DOI: 10.1097/sap.0000000000002767
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Evidence-Based Approach to Timing of Nerve Surgery

Abstract: Events causing acute stress to the health care system, such as the COVID-19 pandemic, place clinical decisions under increased scrutiny. The priority and timing of surgical procedures are critically evaluated under these conditions, yet the optimal timing of procedures is a key consideration in any clinical setting. There is currently no single article consolidating a large body of current evidence on timing of nerve surgery. MEDLINE and EMBASE databases were systematically reviewed for clinical data on nerve … Show more

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Cited by 21 publications
(22 citation statements)
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References 216 publications
(470 reference statements)
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“…The timing of surgery is considered an important factor for optimal return of sensation [29]. A recent publication suggested that acute repair should be performed within 14 days of injury [30]. In our study 124 patients (12%) waited over 7 days for nerve repair and 50 patients (5%) waited more than 14 days.…”
Section: Plos Onementioning
confidence: 64%
“…The timing of surgery is considered an important factor for optimal return of sensation [29]. A recent publication suggested that acute repair should be performed within 14 days of injury [30]. In our study 124 patients (12%) waited over 7 days for nerve repair and 50 patients (5%) waited more than 14 days.…”
Section: Plos Onementioning
confidence: 64%
“…109,[116][117][118] A recent review by MacKay et al recommended that after blunt trauma or GSW, if the zone of injury is clearly established, immediate exploration and peripheral nerve repair may be warranted as to avoid long-term nervous insufficiency. 119 The advantages of early exploration include improved outcomes and shorter graft length requirements, which may be attributable to avoiding dense scar tissue formation and intraneural edema. Ultimately, the decision is subject to clinical judgment and individual patient/injury characteristics.…”
Section: Treatment Of Concomitant Injuriesmentioning
confidence: 99%
“…However, when the zone of injury is unclear, a wait time of 2 to 3 weeks is advised. 119 Penetrating injuries that result in vascular injury above the knee and fracture to the proximal tibia are at high risk of causing compartment syndrome. 120…”
Section: Treatment Of Concomitant Injuriesmentioning
confidence: 99%
“…Although the window for repair and functional recovery is generally accepted as within 12 to 15 months, it is ideal for motor nerve regeneration and target reinnervation to actively occur within 3 to 4 months. Some evidence suggests this is a critical time point, after which regeneration outcomes start to become poor [4] . Of note, timing is different with sensory nerves.…”
Section: Overview Of Nerve Injuries and Repairmentioning
confidence: 99%