Everyday Problems With Executive Dysfunction and Impulsivity in Adults Recovering From Methamphetamine Addiction

Ellis, Carilyn C.; Hoffman, William F.; Jaehnert, Sarah; Plagge, Jane M.; Loftis, Jennifer M.; Schwartz, Daniel L.; Huckans, Marilyn

doi:10.1097/adt.0000000000000059

Cited by 19 publications

(14 citation statements)

References 33 publications

(35 reference statements)

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“…QOL, the perception of one's position in life, comprises physical (energy, pain, and difficulties engaging with activities of daily living and work), psychological (affect, self‐perception, perceived cognition), social (personal relationships, social and sexual activity) and environmental (financial/accommodation stability and access to services/information) domains . Previous research has identified that MD is associated with poorer QOL in at least three of these domains: physical (physical and medical impairment ), psychological (diminished emotional control , high rates of anxiety, depression and psychosis ) and social (high interpersonal conflict and lower social support ). Improvement in such domains is a key focus for treatment, with QOL and wellbeing identified as key indicators of addiction recovery and treatment success .…”

Section: Introductionmentioning

confidence: 99%

“…In social settings, impulsive action is significantly predictive of language difficulties and problems with planning recreational activities . Psychological aspects of QOL are also impacted; diminished emotional self‐control has been observed in MD individuals with heightened impulsive choice and action . Impulsive action is also associated with deficits in managing transportation and finances , medication management, completing chores around the home and reduced activities of daily living performance .…”

Section: Introductionmentioning

confidence: 99%

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Impulsivity predicts poorer improvement in quality of life during early treatment for people with methamphetamine dependence

et al. 2017

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Impulsivity predicts poorer improvement in quality of life during early treatment for people with methamphetamine dependence

et al. 2017

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“…Both impulsivity and working memory are individually predictive of substance use and are consistently impaired in individuals with MUD (Ellis et al 2016;Zhong et al 2016). There is a strong theoretical rationale for the link between impulsivity, working memory and drug use in individuals with MUD; however, past research has been limited.…”

Section: Introductionmentioning

confidence: 99%

Working memory predicts methamphetamine hair concentration over the course of treatment: moderating effect of impulsivity and implications for dual‐systems model

et al. 2017

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High impulsivity and poor executive function are characteristic of methamphetamine use disorder. High arousal in the impulsive system has been proposed to compromise the executive system's regulating ability (i.e. the dual-systems model). While interaction between these variables may partly explain poor treatment outcomes associated with methamphetamine use disorder, previous research has tended to examine each factor separately. We investigated whether high impulsivity (measured with an impulsive choice task) and poor executive function (measured with a working memory task) predict methamphetamine use (determined by hair sample) in the 6 weeks following treatment commencement. We also investigated whether impulsive choice moderates the relationship between working memory and methamphetamine use. One hundred and eight individuals with methamphetamine use disorder (75 percent male) were tested within 3 weeks of commencing treatment; 80 (74 percent) were followed up 6 weeks following baseline testing. Cognitive measures significantly predicted drug use after controlling for nuisance variables. Working memory was a significant predictor, while impulsive choice was not. The interaction model included working memory as a predictor and impulsive choice as a moderator. This model was significant, as was the interaction term. Working memory significantly predicted levels of methamphetamine use in early treatment, and impulsive choice moderated this relationship. Those with working memory deficits are particularly vulnerable to using greater amounts of methamphetamine. As working memory increased methamphetamine use decreased among individuals with low/medium delay discounting. Pre-treatment cognitive testing may identify patients at high risk, while remediation of working memory function may be a treatment target for reducing methamphetamine use.

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“…A recent study supports this finding, as not only were treatment-seeking MA dependent individuals less behaviorally inhibited on objective measures of impulsivity, but they also had higher levels of subjective impulsivity relative to controls (Ellis, et al, 2016). A common measure used to assess subjective impulsivity is the Barratt Impulsiveness Scale (BIS-11), which has been divided into three second-order factors, including Attentional, Motor, and Non-planning impulsiveness (Patton, Stanford, & Barratt, 1995).…”

Section: Introductionmentioning

confidence: 70%

“…First use of MA occurs at about 22 years of age (Center for Behavioral Health: Statistics and Quality, 2015), during the transition between late adolescence and emerging adulthood. While many factors may be associated with the initiation and maintenance of MA use, impulsivity is a personality trait found to be higher in MA users relative to healthy controls (Ballard, et al, 2015; Ellis, et al, 2016; Hoffman, et al, 2006). …”

Section: Introductionmentioning

confidence: 99%

Self-reported attentional and motor impulsivity are related to age at first methamphetamine use

Cservenka

Ray

2017

Addictive Behaviors

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Introduction Methamphetamine (MA) users report higher levels of impulsivity relative to healthy controls, which may either result from, or precede, their substance use. Further, there is evidence that female MA users may be more impulsive than male MA users prior to MA use. Thus, the goal of the current study was to determine whether different subtraits of self-reported impulsivity are significantly related to age at first MA use, controlling for total years of MA use. Methods A community sample of MA users was recruited for this study (N = 157; 113 males, 44 females). The Barratt Impulsiveness Scale (BIS-11) was used to assess self-reported impulsivity on three subscales (Attentional, Motor, Non-planning). Age at first MA use served as the dependent variable in a series of multiple regression models with BIS-11 subscales, sex, and their interaction as independent variables, controlling for total years of MA use. Results Attentional and Motor impulsivity were significantly related to age at first MA use when controlling for total years of MA use (Attentional: p = 0.008; Motor: p = 0.003). Conclusions Individuals who reported higher Attentional and Motor impulsivity started using MA at an earlier age, which could suggest that impulsivity levels may be an important marker of vulnerability towards MA use. These findings indicate that prevention efforts may be targeted towards individuals who report high levels of Attentional and Motor impulsivity, as they may be at greatest risk for earlier initiation of MA use.

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Everyday Problems With Executive Dysfunction and Impulsivity in Adults Recovering From Methamphetamine Addiction

Cited by 19 publications

References 33 publications

Impulsivity predicts poorer improvement in quality of life during early treatment for people with methamphetamine dependence

Impulsivity predicts poorer improvement in quality of life during early treatment for people with methamphetamine dependence

Working memory predicts methamphetamine hair concentration over the course of treatment: moderating effect of impulsivity and implications for dual‐systems model

Self-reported attentional and motor impulsivity are related to age at first methamphetamine use

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