Event DAS-444Ø6-6 soybean grown in Brazil is compositionally equivalent to non-transgenic soybean

Fast, Brandon J.; Galan, Maria Paula; Schafer, Ariane C.

doi:10.1080/21645698.2016.1184815

Cited by 7 publications

(2 citation statements)

References 7 publications

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“…Previous analyses of soybean using six categories of analytes illustrated a reasonable spread of analyte concentrations along the regression lines and a subsequently adequate depiction of profiles within each analyte category (Fast et al ., ). A similar situation was observed here for maize (Figures ).…”

Section: Resultsmentioning

confidence: 97%

Stacking transgenic event DAS‐Ø15Ø7‐1 alters maize composition less than traditional breeding

Herman¹,

Fast²,

Scherer³

et al. 2017

Plant Biotechnology Journal

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SummaryThe impact of crossing (‘stacking’) genetically modified (GM) events on maize‐grain biochemical composition was compared with the impact of generating nonGM hybrids. The compositional similarity of seven GM stacks containing event DAS‐Ø15Ø7‐1, and their matched nonGM near‐isogenic hybrids (iso‐hybrids) was compared with the compositional similarity of concurrently grown nonGM hybrids and these same iso‐hybrids. Scatter plots were used to visualize comparisons among hybrids and a coefficient of identity (per cent of variation explained by line of identity) was calculated to quantify the relationships within analyte profiles. The composition of GM breeding stacks was more similar to the composition of iso‐hybrids than was the composition of nonGM hybrids. NonGM breeding more strongly influenced crop composition than did transgenesis or stacking of GM events. These findings call into question the value of uniquely requiring composition studies for GM crops, especially for breeding stacks composed of GM events previously found to be compositionally normal.

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Section: Resultsmentioning

confidence: 97%

Stacking transgenic event DAS‐Ø15Ø7‐1 alters maize composition less than traditional breeding

Herman¹,

Fast²,

Scherer³

et al. 2017

Plant Biotechnology Journal

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“…6 This statistical method has also been used to evaluate the compositional equivalence of maize breeding stacks containing event DAS-Ø15Ø7-1 and non-GE maize, compositional equivalence of soybean event DAS-444Ø6-6 and non-GE soybean, and endogenous allergen level equivalence of DAS-81419-2, DAS-444Ø6-6, DAS-81419-2 × DAS-444Ø6-6, and DAS-68416-4 × MON 89788 soybean and non-GE soybean. [7][8][9] MATERIALS AND METHODS…”

Section: Introductionmentioning

confidence: 99%

Transgene-product expression levels in genetically engineered breeding stacks are equivalent to those of the single events

Cerqueira¹,

Fast

Silveira³

et al. 2019

GM Crops & Food

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Transgene product expression levels are measured in genetically engineered (GE) crops containing single transformation events and the measured expression levels are then utilized in food, feed, and environmental safety assessments as part of the requirements for deregulation of the event. Many countries also require measurement of expression levels and safety assessments for GE breeding stacks, even though the breeding stacks are composed of single events that have been previously assessed. Transgene product expression levels were measured in tissues of maize, soybean, and cotton breeding stacks and each of their component single events. Expression levels in the breeding stacks were plotted against expression levels in the single events to quantify the ability of the single events to predict transgene product expression levels in the breeding stacks. These results indicate that transgene product expression levels in single events are a reliable indicator of expression levels in breeding stacks. Based on these results it is concluded that safety assessments for breeding stacks can be conducted using transgene product expression levels from single events.

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Transgenesis affects endogenous soybean allergen levels less than traditional breeding

Hill¹,

Fast²,

Herman³

2017

Regulatory Toxicology and Pharmacology

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Event DAS-444Ø6-6 soybean grown in Brazil is compositionally equivalent to non-transgenic soybean

Cited by 7 publications

References 7 publications

Stacking transgenic event DAS‐Ø15Ø7‐1 alters maize composition less than traditional breeding

Stacking transgenic event DAS‐Ø15Ø7‐1 alters maize composition less than traditional breeding

Transgene-product expression levels in genetically engineered breeding stacks are equivalent to those of the single events

Transgenesis affects endogenous soybean allergen levels less than traditional breeding

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