Even Short-Term hGH Treatment Induces Endocrine Changes in the Elderly

Strollo, Felice; Semprini, A; Strollo, G; Morè, M.; Bollanti, Lucilla; Ciarmatori, A.; Pizzabiocca, D.; Mangrossa, N; Riondino, G

doi:10.1007/978-1-4613-8372-7_26

Cited by 1 publication

(1 citation statement)

References 26 publications

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“…A further important point is that some endocrine systems seem to undergo changes in space resembling those observed during senescence, but after space-flight recovery always occurs within weeks or months after return [46,47,48,49,50], thus suggesting space as a possible experimental model for the study of reversible ageing processes. This applies especially to systems regulating bone and muscle metabolism and reproduction [51,52], but is also true for the immune, the neurosensory or the cardiovascular system.…”

Section: The Hypothalamic-pituitary-gonadal Axis (Hpga)mentioning

confidence: 99%

Adaptation of the human endocrine system to microgravity in the context of integrative physiology and ageing

Strollo

2000

Pflügers Arch - Eur J Physiol

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This review deals with changes occurring in space in different endocrine systems. Sections are dedicated to hormones involved in bone remodelling, the hypothalamic-pituitary-adrenal axis, the hypothalamicpituitary-thyroid axis, pancreatic hormones, the hypothalamic-pituitary-gonadal axis and the hypothalamicpituitary-somato-mammotropic system. In space, most systems -especially those regulating bone/muscle metabolism and reproduction -undergo changes resembling those observed during senescence, but recover within weeks or months after return. This suggests space as a possible experimental model for the study of "reversible ageing processes". Studying ageing through space technology might give us the opportunity to combine the holistic view of integrative physiology with the most ambitious goal of the present scientific community, i.e. to yield successful ageing by promoting chronic disease prevention studies and by optimizing safe, anti-ageing therapeutic protocols.

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Section: The Hypothalamic-pituitary-gonadal Axis (Hpga)mentioning

confidence: 99%

Adaptation of the human endocrine system to microgravity in the context of integrative physiology and ageing

Strollo

2000

Pflügers Arch - Eur J Physiol

View full text Add to dashboard Cite

show abstract

Even Short-Term hGH Treatment Induces Endocrine Changes in the Elderly

Cited by 1 publication

References 26 publications

Adaptation of the human endocrine system to microgravity in the context of integrative physiology and ageing

Adaptation of the human endocrine system to microgravity in the context of integrative physiology and ageing

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