Evaporated fraction of thujopsene from Thujopsis dolabrata starves cancer cells via PKM2 Anti-tumor effect of the volatile components of Thujopsis dolabrata
Abstract:Objective
Many cancer patients need for new treatment options with lower side effects. Herein, we report on the antitumor effect of thujopsene derived from the volatile components of Thujopsis dolabrata(asunaro).
Methods
The antitumor effect of the asunaro essential oil was analyzed using MTT (3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide) assay and in vivo cancer metastasis model. Thujopsene was isolated from asunaro essential oil by liquid chromatography, and the tumor growth inhibitory mechan… Show more
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