Evaluation the correlation between anti-spike protein IgG antibody titers against SARS-CoV-2 Prototype and different Omicron variants by ELISA and neutralization activity
Abstract:Evaluating the IgG titers targeting the S protein of SARS-CoV-2 by ELISA
assays have been used in the development of several anti-SARS-CoV-2
vaccines in China. It is unclear whether the IgG levels against S
protein tested by ELISA can monitor immune evasion against different
Omicron variants. In the study, 88 recipients immunized with three doses
of a COVID-19-inactivated vaccine were enrolled, whose serum samples
were collected within 2 months after the third immunization. The IgG
antibody levels were detecte… Show more
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