Evaluation of Zidovudine, Lamivudine and Nevirapine Plasma Concentrations and Factors influencing their Plasma Drug Exposure in Children Aged 2–14 Years Living with HIV at the Lagos University Teaching Hospital
Abstract:Background: Plasma concentrations of antiretroviral drugs have become important determinants of treatment success, treatment failure and toxicity. There is a paucity of antiretroviral plasma concentration data in our local paediatric human immunodeficiency virus (HIV) literature in Nigeria. Objective: To evaluate plasma concentrations of zidovudine, lamivudine, and nevirapine after 2 years of combination therapyand to determine factors that influence plasma drug exposure in children aged 2–14 years living wit… Show more
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