Evaluation of weight retention four weeks after delivery as a risk factor for gestational diabetes mellitus in a subsequent pregnancy

Abstract

We aimed to assess the association between postpartum weight retention (PPWR) in the fourth week after delivery and the risk of gestational diabetes mellitus (GDM) in a subsequent pregnancy. MethodsWe performed a retrospective cohort study of the obstetric records of women who gave birth to their second singleton between 32 and 41 weeks of gestation at the National Hospital Organization Kofu National Hospital between January 2013 and September 2019. The exclusion criteria were missing data, twin pregnancy, diabetes in pregnancy, and delivery before 22 weeks in the first pregnancy. We calculated PPWR as the BMI 4 weeks after the first birth minus the BMI before the first pregnancy and grouped the subjects into the stable PPWR (gain of <1 BMI unit) and non-stable PPWR groups (gain of �1 BMI units). We used the χ 2 test and multivariable logistic regression analysis to investigate the association between weight retention at the postpartum checkup and GDM. ResultsWe included 566 women in this study (mean age, 31.7±4.8 years; mean maternal pre-pregnancy BMI, 21.3±3.5 kg/m 2 ; term delivery, n = 544 [96.1%]). The overall prevalence of GDM during the second pregnancy was 7.4% (42/566), and 33.9% (192/566) of women had stable PPWR. Non-stable PPWR was not significantly associated with GDM in the second pregnancy (adjusted odds ratio, 1.93; 95% confidence interval, 0.84-4.46) after controlling for each variable. ConclusionPPWR measured in the fourth week after delivery was not associated with an increased risk of GDM in the second pregnancy.

Changes in maternal anthropometric measurements in the first postpartum month and associated factors

“…During follow-up period, mothers with GDM had a lower increase in fatmass ratio in the first month after birth, whereas, weight and BMI changes were not different. Similarly, a singlecenter study did not find a significant relationship between postpartum weight retention four weeks after delivery and GDM (Shinohara et al, 2020). However, there are some differences in weight gain during pregnancy and the occurrence of GDM.…”

“…The pregnancy and postpartum periods are critical because they can significantly affect a mother's long-term weight management and predispose a mother to chronic diseases later in life (Endres et al, 2015). Postpartum maternal weight retention is related to an increased incidence of adverse neonatal and maternal outcomes (Ratnasiri et al, 2019;Shinohara, Amemiya, & Takizawa, 2020). Postpartum weight retention was associated with increased risks of long-term obesity for women (Joo et al, 2020).…”