1968
DOI: 10.1056/nejm196805302782201
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Evaluation of “Virus-Like” Particles in the Plasmas of 255 Patients with Leukemia and Related Diseases

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Cited by 28 publications
(3 citation statements)
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“…However, it has also been shown that there is no dif ference in type or quantity of virus-like particles found in plasm asfrom patients with leukemia and lymphoma and in normalcontrols. 82 Unlike the animal and laboratory evi dence suggesting a virus etiology of human leukemia, the epidemiologic evi dence is largely negative.83'84Among dizygous twins the concordance rate for leukemia is almost zero. However, both the dizygous co-twins and the siblings of affected children have about four times the leukemia risk of the general popula tion.…”
Section: Human Cancermentioning
confidence: 98%
“…However, it has also been shown that there is no dif ference in type or quantity of virus-like particles found in plasm asfrom patients with leukemia and lymphoma and in normalcontrols. 82 Unlike the animal and laboratory evi dence suggesting a virus etiology of human leukemia, the epidemiologic evi dence is largely negative.83'84Among dizygous twins the concordance rate for leukemia is almost zero. However, both the dizygous co-twins and the siblings of affected children have about four times the leukemia risk of the general popula tion.…”
Section: Human Cancermentioning
confidence: 98%
“…These eight investigations were drawn from a total of 50 case clusters involving childhood (under age 15 years) leukemia or lymphoma in US communities that were studied by the Centers for Disease Control and Prevention in cooperation with state and local health agencies and the National Cancer Institute. Limited laboratory studies were conducted (4,29,30), but none produced useful leads. Aside from the eight communities described here, little was found to link individual cases beyond increased case frequencies.…”
mentioning
confidence: 99%
“…άνθρωπου είναι ανάλογοι μέ τύπους λευχαιμίας στα ζώα (Henle, 1968). Σωματίδια πού μοιάζουν μέ ιούς έχουν παρατηρηθή μέ τό ηλεκτρονικό μικροσκόπιο στό αίμα, τόν μυελό των οστών καί τους λεμφαδένες ατόμων πασχόντων άπό λευχαιμία (Dmoshowski et al, 1967, Newell et al, 1968. " Αν και αυτά τά σωματίδια μοιάζουν μέ τους 'ιούς, οι όποιοι προκαλούν τή λευχαιμία στά ζώα, δέν έχει γίνει δυνατό νά ταυτοποιηθοΰν μέ βάσι τά μορφολογικά τους χαρακτηριστικά καί πολλοί υποστηρίζουν, ότι είναι οργανισμοί του τύπου του μυκοπλάσματος (Gilbey andPollard, 1967, Grace et al,, 1965).…”
Section: θεωρία τής ϊογενοϋς αιτιολογίαςunclassified