Evaluation of uterine temperament in iranian infertile women using a quantitative instrument for uterine temperament detection

Tansaz, Mojgan; Sohrabvand, Farnaz; Adhami, Samira; Keshavarz, Mansoor; Bioos, Soodabeh; Mokaberinejad, Roshanak; Yavari, Maryam

doi:10.4103/ijpvm.ijpvm_64_17

Cited by 5 publications

(1 citation statement)

References 17 publications

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“…In recent studies, the most common temperament found in patients with infertility complaints was cold and wet. It was also confirmed that the temperament of the uterus is related to the hot/cold temperament of the body and pelvic width (14,15). Folk remedy emphasizes the hot (harr) property of U. pilulifera, suggesting that it can potentially increase the quantity of semen and enhance sexual libido and arousal in both males and females.…”

Section: Diminished Ovarian Reserve (Dor) Is Used Tomentioning

confidence: 69%

Urtica pilulifera L. seed extract promotes folliculogenesis and alleviates the diminished ovarian reserve in the Balb/c mice model: An experimental study

Hekmat,

Sharifzadeh,

Toliyat

et al. 2024

IJRM

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Background: Urtica pilulifera L. seed (UPS) is a Persian traditional medicine prescription that positively affects female infertility. Objective: This study aimed to evaluate the beneficial effects of UPS on a diminished ovarian reserve (DOR) model induced by cyclophosphamide in Balb/c mice. Materials and Methods: A single intraperitoneal (75 mg/kg) of cyclophosphamide was administered to establish a DOR model. 25 female Balb/c mice (6–8 wk, 25 ± 2 gr) were randomly divided into 5 groups (n = 5/each), including control (normal saline), model (DOR), DOR+50, DOR+100, and DOR+200 (mg/kg UPS, gavage) groups for 14 days. The levels of follicle-stimulating hormone, luteinizing hormone, estradiol, malondialdehyde, superoxide dismutases, apoptosis, and histopathological alterations were analyzed. Gas chromatography-mass spectrometry analysis was performed to identify the phytochemicals of the UPS. Results: It was observed that the UPS extract reduced malondialdehyde concentration and apoptosis in the DOR model as well as enhanced superoxide dismutases activity in the ovaries in a dose-dependent manner. Moreover, it exerted a modulatory effect on steroidal hormones such as follicle-stimulating hormone, luteinizing hormone, and estradiol. The histopathological analysis revealed the therapeutic potential of the UPS extract. The main chemical components of UPS were linoleic acid (59.25%), n-hexadecanoic acid (10.36%), and oleic acid (8.29%). Conclusion: The results indicated that the UPS extract has therapeutic potential in the DOR model. This potential is attributed to the reduction of oxidative stress, modulation of apoptosis, and regulation of steroidal hormones that may be associated with the observed beneficial effects of fatty acids on fertility improvement. Key words: Apoptosis, Fatty acids, Female infertility, Herbal medicine, Persian medicine, Oxidative stress.

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Section: Diminished Ovarian Reserve (Dor) Is Used Tomentioning

confidence: 69%

Urtica pilulifera L. seed extract promotes folliculogenesis and alleviates the diminished ovarian reserve in the Balb/c mice model: An experimental study

Hekmat,

Sharifzadeh,

Toliyat

et al. 2024

IJRM

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A new model for estimating basal metabolic rate (BMR) using temperament in traditional Persian medicine (TPM)

Kafaee,

Daviran,

Heydari

et al. 2023

ADV TRADIT MED (ADTM)

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Experimental and Computational Approaches for the Classification and Correlation of Temperament (Mizaj) and Uterine Dystemperament (Su’-I-Mizaj Al-Rahim) in Abnormal Vaginal Discharge (Sayalan Al-Rahim) Based on Clinical Analysis Using Support Vector Machine

Sultana¹,

Begum²,

Saeedi³

et al. 2022

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The temperament (Mizaj) of the body is an essential constituent for health conservancy and diagnosis of several diseases. Hence, general body temperament and uterine dystemperament (Su’-i-Mizaj) with abnormal vaginal discharge (Salayan al-Rahim) need evaluation. In addition, we also applied a computational intelligence technique for enhancing scientific validity to classify the warm-cold and wet-dry temperaments. This trial included a total of 66 participants with a vaginal discharge of reproductive age. Data included demographic characteristics of the participants, symptoms associated with vaginal discharge, women’s general temperament, and symptoms of uterine dystemperament. Correlation between general body temperament and age, abnormal vaginal discharge, and its associated symptoms was also performed. Additionally, we used the Support Vector Machine-Radial Basis Function (SVM-RBF) model to classify the warm-cold and wet-dry temperaments. Warm general temperament was highly prevalent (77.27%), followed by moderate (19.69%) on the warm-cold temperament scale. In wet-dry temperament, moderate general body temperament (50%) was more prevalent. In warm-cold and wet-dry scores, 78.78% and 74.24% had warm and wet uterine dystemperament, respectively. The age and symptoms were correlated with general temperament. A strong positive correlation was found between warm general temperament and warm dystemperament of the uterus (r = 0.40, p < 0.009). In addition, our SVM-RBF CV-5 classification model achieved the highest accuracy (99.2%). Our results showed that vaginal discharge is more common in warm general temperament and warm-wet dystemperament of the uterus. The same has been proven by computational intelligence. Nevertheless, vaginal discharge can also happen in normal and other temperaments.

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Evaluation of uterine temperament in iranian infertile women using a quantitative instrument for uterine temperament detection

Cited by 5 publications

References 17 publications

Urtica pilulifera L. seed extract promotes folliculogenesis and alleviates the diminished ovarian reserve in the Balb/c mice model: An experimental study

Urtica pilulifera L. seed extract promotes folliculogenesis and alleviates the diminished ovarian reserve in the Balb/c mice model: An experimental study

A new model for estimating basal metabolic rate (BMR) using temperament in traditional Persian medicine (TPM)

Experimental and Computational Approaches for the Classification and Correlation of Temperament (Mizaj) and Uterine Dystemperament (Su’-I-Mizaj Al-Rahim) in Abnormal Vaginal Discharge (Sayalan Al-Rahim) Based on Clinical Analysis Using Support Vector Machine

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