Evaluation of two rapid antigen assays, BioStar Strep A OIA and Pacific Biotech CARDS O.S., and culture for detection of group A streptococci in throat swabs

Abstract

REFERENCES 1. Dale, J. C., E. A. Vetter, J. M. Contezac, L. D. Iverson, P. C. Wollan, and F. R. Cockerill III. 1994. Evaluation of two rapid antigen assays, BioStar Strep A OIA and Pacific Biotech CARDS O.S., and culture for detection of group A streptococci in throat swabs. J. Clin. Microbiol. 32:2698-2701. 2. Daly, J. A., E. K. Korgenski, A. C. Munson, and E. Llausas-Magana. 1994. Optical immunoassay for streptococcal pharyngitis: evaluation of accuracy with routine and mucoid strains associated with acute rheumatic fever outbreak in the intermountain area of the United States. J. Clin. Microbiol. 32:531-532. 3. Della-Latta, P., S. Whittier, M. Hosmer, and F. Agre. 1994. Rapid detection of group A streptococcal pharyngitis in a pediatric population with optical immunoassay. Pediatr. Infect. Dis. J. 13:742-743. 4. Facklam, R. R. 1976. A review of the microbiological techniques for the isolation and identification of streptococci. CRC Crit. Rev. Clin. Lab. Sci. 6:287-317. 5. Facklam, R. R., and J.

The utility of rapid antigen detection testing for the diagnosis of streptococcal pharyngitis in low-resource settings

“…RADTs may provide significant cost-benefit advantages if the test sensitivity is adequately high. [36][37][38] In the USA, as at our participating sites, the cost of a RADT (US$5-10) is somewhat lower than the cost of a throat culture (US$ [15][16][17][18][19][20]. 39 There were several limitations to our study.…”

“…The RADT has internal positive and negative controls and has a reported sensitivity range of 79.5-98.1% and specificity of 96.9-99.0%, compared to throat culture. [15][16][17]20,21…”

“…3 To assess the utility of RADTs in varied clinical settings, we compared the performance of a commercially available rapid antigen detection test-the STREP A OIA MAX (Thermo Biostar/ Inverness Medical Professional Diagnostics, Princeton, NJ, USA)with standard throat culture, in Brazil, Croatia, Latvia, and Egypt. [14][15][16][17] To our knowledge, this is the first prospective multicountry evaluation of a RADT for GAS pharyngitis using a single standard protocol.…”

Treatment of Streptococcal Pharyngitis With Once-Daily Amoxicillin Versus Intramuscular Benzathine Penicillin G in Low-Resource Settings: A Randomized Controlled Trial

“…This rapid test had internal positive and negative controls and has a reported sensitivity range of 79.5% to 98.1% and specificity of 96.9% to 99.0%, compared with throat culture. [29][30][31][32][33] Both sites independently were provided with uniform training and regular site visits to ensure uniform laboratory procedures for both throat culture and rapid tests.…”