“…Central catheter-related infection is usually because The most severe infections occur when thrombi surrounding the catheter become infected, thus caus-of contamination of some portion of the catheter (external, subcutaneous or intravenous (i.v.)). Organisms ing septic thrombosis of the central vein or the pulmonary artery [26,27]. With septic thrombosis, the colonizing the patient's skin at the insertion site are the most frequent contaminants of the catheter [16], central vein or the pulmonary artery becomes an 'abscess', discharging pathogens into the bloodstream.…”