lose monitoring of the peripheral circulation is critical for the management of intensive care unit (ICU) patients, including particularly those who have just had open-heart surgery. Although peripheral temperature monitoring of the extremities is a simple method to diagnose peripheral circulatory disturbance, it does not provide a quantitative assessment. The systemic vascular resistance (SVR) index (SVRI) is an objective and standard measure of the peripheral circulation, but calculation of SVRI requires the determination of cardiac output (CO; in L/min) through invasive examination or the use of sophisticated equipment. CO is estimated non-invasively from oxygen uptake during exercise, 1 but the calculation of SVR needs central venous pressure (CVP: in mmHg) or mean right atrial pressure measurements. 2 Therefore, the development of a quantitative method to evaluate peripheral circulatory disturbance non-invasively is important.Resistive index (RI) is a parameter that not only indicates the absolute value of blood flow velocity but also reflects changes in Doppler waveforms. In the urology field, RI is used in the evaluation of the severity of impaired blood circulation following renal transplantation and progressive nephropathy. However, RI has mainly been used for evaluating blood flow to a target organ, but not for hemodynamics. In patients with extreme hemodynamics, including those who have had open-heart surgery and following an emergency, it is very important to know the impairment of the peripheral circulation; therefore, if RI could be used simply to quantify systemic blood vessel resistance, it could be an important parameter for circulation control, based on a different perspective from that of cardiac output and oxygen saturation of mixed-venous blood. Here, we measured RI in the upper extremity arteries, examined the most effective point of measurement, and determined whether this technique allows for the quantitative evaluation of peripheral circulatory disturbance.
Methods
Measurements of RIAt each measurement point, a 7.5 MHz probe was positioned on the measurement surface and a target artery (simulated peripheral artery in vitro) was imaged in B mode. A site with the minimum ultrasonic incidence angle was selected in the artery on display and pulsed Doppler ultrasonography was conducted. The systolic maximum velocity (Vmax) and diastolic minimum velocity (Vmin) of the pulsed Doppler waveforms were determined and Background To explore an alternative to the systemic vascular resistance index (SVRI) for monitoring peripheral circulation in patients in the intensive care unit (ICU), the resistive index (RI) in the upper extremity arteries was measured by using surface Doppler ultrasound.
Methods and ResultsThe correlation between RI and vascular resistance was assessed in vitro using a vessel phantom in a Donovan-type mock circulation system. In addition, 15 ICU patients who had undergone open-heart surgery were studied. Mean arterial pressure, central venous pressure and cardiac output were measu...