Contamination of industrial wastewater with dyes poses a significant threat to public health. Extensive efforts have been dedicated to mitigating the presence of dyes in aquatic ecosystems. This research focuses on the degradation of the azo-type NOVACRON® C-4B reactive red dye generated from the textile industry through ultraviolet (UV) radiation in conjunction with hydrogen peroxide (H2O2). This research investigated multiple variables, including dye concentration, pH levels, H2O2 concentration, UV exposure duration, and UV power, to evaluate their influence on the degradation process. The maximum dye degradation of 86 and 78% chemical oxygen demand (COD) reduction was achieved for 50 mg/L dye concentration at pH 4, 0.9 mL of H2O2, and 120 min of UV irradiation time. The degradation results were compared with other advanced oxidation processes to check the effectiveness of this system. It has been demonstrated that the UV/H2O2 system is effective and capable of degrading the azo dyes such as NOVACRON® C-4B reactive red dye effectively compared with other conventional biological and physiochemical treatment processes.