Evaluation of Three Human-Use Glucometers for Blood Glucose Measurement in Dogs

Abstract

Background. Glucometers or portable sensors are used to quickly measure blood glucose at low cost. They are used in veterinary practice and by guardians to monitor diseases that require, as in diabetes mellitus. However, not all commercially available glucometers (human and veterinary) are suitable for this purpose. Hypotheses/Objectives. The objective was to evaluate the analytical and clinical precision of three human-use portable glucometers. Animals. This study evaluated 115 samples in three glycemic ranges (hypoglycemia, normoglycemia, and hyperglycemia) from 82 dogs recruited from veterinary services. Methods. The portable glucometers are the FreeStyle Freedom Lite®, FreeStyle Optium Neo®, and On Call Plus® models. Glucometer results were compared with the enzymatic colorimetric glucose oxidase laboratory reference method. Using descriptive and comparative statistical analysis, there were correlations between these devices and the standard method, ISO 15197 : 2003 and ISO 15197 : 2013 standards, and error grid analysis. Results. Only the Freedom Lite® device observed a statistical difference when compared with the reference method. Despite the underestimated glucose concentrations assessed with humane devices, all three tested herein showed a positive coefficient. However, none of these achieved all ISO guidelines. Conclusion and Clinical Importance. Although there was wide use of portable humane devices for dog glucose measurements on routine, the results are generally inferior when compared to the reference method. The FreeStyle Optium Neo® glucometer obtained the best result and is therefore the best option among the glucometers evaluated; however, for the first attendance on veterinary routine, all three glucometers had a satisfactory glucose measurement until the reference method availability.

Medidas comportamentais e fisiológicas: correlação e relevância para avaliação do bem-estar de bovinos de corte

“…This is useful, because in addition to allowing the energy metabolism to be monitored, it can now be used to determine the animal's degree of stress and try to reduce it (Mair et al, 2016). Different portable glucometers have been evaluated in dogs, with similar results to those obtained using the reference method, showing that there is no significant statistical difference between the various methodologies (Santos et al, 2022).…”

Evaluación del perfil lipídico y niveles de glucosa en perros obesos

“…Para evaluar los niveles de glucosa en perros se emplean varios métodos, entre los que podemos mencionar los medidores de glucosa en sangre portátiles (PBGM), como el FreeStyle Freedom Lite®, el FreeStyle Optium Neo® y el On Call Plus®, que se utilizan con frecuencia, y el FreeStyle Optium Neo®, los cuales muestran los mejores resultados entre los evaluados (Dos Santos et al, 2022). También se han utilizado monitores de glucosa intersticial (IgM), que han demostrado que las mediciones de glucosa son clínicamente aceptables en comparación con las de los PBGM en perros jóvenes (Vigh et al, 2023).…”

“…Las pruebas de laboratorio para evaluar los niveles de glucosa en perros se pueden realizar utilizando varios métodos. Se ha descubierto que los glucómetros portátiles diseñados para uso humano proporcionan resultados precisos al medir la glucosa en sangre en perros, y los estudios muestran una buena correlación entre los niveles de glucosa en sangre capilar y venosa (Dos Santos et al, 2022). Sin embargo, si bien los glucómetros portátiles ofrecen comodidad y rentabilidad, es posible que no siempre cumplan con las directrices de la ISO en materia de precisión (Ismail-Hamdi et al, 2021).…”

Impact on result interpretation of correct and incorrect selection of veterinary glucometer canine and feline settings

“…Several investigators report that treatment decisions would likely be unaltered if a human glucometer was used 8,9,17,19,20,23,31 ; however, others report substantial differences in accuracy, which could lead to altered treatment decisions. 3,5,6,11,18,29 Overall, veterinary glucometers may be more accurate than human glucometers for measurement of glucose in dogs and cats, 5,19,20,28,35 although findings have varied. 5,18,20,33 The AlphaTrak 2 veterinary glucometer (Zoetis) reports plasma glucose equivalent and requires correct coding of the meter for the patient species.…”