Abstract:Enolase (2-phospho-D-glycerate hydrolase) enzyme has been characterized extensively and approved as a molecular drug target for rational drug discovery in apicomplexan such as Plasmodium spp., Toxoplasma gondii but not in the Theileria parva which causative agent of East Coast Fever engender serious economic losses. For the aim of identifying a key drug target, we have analyzed Theileria parva's enolase sequence and we have constructed three-dimensional structure of that enolase and mammalian host Bos taurus e… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.