Evaluation of the World Health Organization standard tourniquet test and a modified tourniquet test in the diagnosis of dengue infection in Viet Nam

Phuong, Cao Xuan Thanh; Nhan, Ngo Thi; Wills, Bridget; Kneen, Rachel; Hà, Nguyễn Thị Thanh; Tuyet, Ta Thi; Huynh, Tran Thi Thanh; Lien, Doan Thi Kim; Solomon, Tom; Simpson, Julie A; White, Nicholas J.; Farrar, Jeremy

doi:10.1046/j.1365-3156.2002.00841.x

Cited by 92 publications

(34 citation statements)

References 9 publications

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“…Similar studies have evaluated TT performance in different groups and places and have had similar results. A study in Vietnamese children reported a specifi city as high as 94% but a sensitivity of only 42% for the TT in diagnosing suspected dengue infection 19 . Another study, this time evaluating suspected dengue infection in adults in Laos, also reported high (84%) specifi city and low (34%) sensitivity 7 .…”

Section: Discussionmentioning

confidence: 99%

Evaluation of the diagnostic value of the tourniquet test in predicting severe dengue cases in a population from Belo Horizonte, State of Minas Gerais, Brazil

Antunes

Oliveira²,

Nunes³

et al. 2013

Rev. Soc. Bras. Med. Trop.

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Introduction:Dengue is prevalent in many tropical and sub-tropical regions. The clinical diagnosis of dengue is still complex, and not much data are available. This work aimed at assessing the diagnostic accuracy of the tourniquet test in patients with suspected dengue infection and its positivity in different classifi cations of this disease as reported to the Information System for Notifi able Disease in Belo Horizonte, State of Minas Gerais, Brazil between 2001 and 2006. Methods: Cross-section analysis of the diagnostic accuracy of the tourniquet test for dengue, using IgM-anti-DENV ELISA as a gold standard. Results: We selected 9,836 suspected cases, of which 41.1% were confi rmed to be dengue. Classic dengue was present in 95.8%, dengue with complications in 2.5% and dengue hemorrhagic fever in 1.7%. The tourniquet test was positive in 16.9% of classic dengue cases, 61.7% of dengue cases with complications and 82.9% of cases of dengue hemorrhagic fever. The sensitivity and specifi city of the tourniquet test were 19.1% and 86.4%, respectively. Conclusions: A positive tourniquet test can be a valuable tool to support diagnosis of dengue where laboratory tests are not available. However, the absence of a positive test should not be read as the absence of infection. In addition, the tourniquet test was demonstrated to be an indicator of dengue severity.

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Section: Discussionmentioning

confidence: 99%

Evaluation of the diagnostic value of the tourniquet test in predicting severe dengue cases in a population from Belo Horizonte, State of Minas Gerais, Brazil

Antunes

Oliveira²,

Nunes³

et al. 2013

Rev. Soc. Bras. Med. Trop.

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“…Esse método não foi realizado em todos os pacientes e apresentou positividade baixa. Isso pode indicar que acrescenta pouco ao diagnóstico de febre hemorrágica do dengue, sendo utilizado principalmente como indicador de presença de fragilidade vascular 9 . Sabe-se que a ocorrência de leucocitose no dengue pode ser considerada como um fator prognóstico associado ao desenvolvimento de complicações 14 .…”

Section: Discussionunclassified

Alterações hematológicas em pacientes com dengue

Oliveira¹,

Pontes

Cunha

et al. 2009

Rev. Soc. Bras. Med. Trop.

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Dengue é uma doença negligenciada de alta morbidade e mortalidade em crianças e adultos, ocorrendo principalmente em regiões tropicais e subtropicais. O objetivo desse trabalho foi avaliar as alterações hematológicas de pacientes com quadro clínico de dengue. Foram estudados 543 prontuários de atendimentos referentes à epidemia pelo vírus tipo 3, ocorrida no ano de 2007, em Campo Grande, Mato Grosso do Sul. Houve predomínio de casos de dengue clássico (90,2%), com quadro clínico leve sem complicações. As principais alterações hematológicas observadas foram a leucopenia (68,3%), plaquetopenia (66,5%), linfocitopenia (67,2%) e presença de linfócitos atípicos (67%). A febre hemorrágica do dengue apresentou plaquetopenia mais prolongada e maior número de linfócitos atípicos, as demais alterações hematológicas apresentaram evolução diária semelhante às encontradas no dengue clássico. As alterações hematológicas observadas no dengue apresentaram-se de acordo com a evolução clínica e gravidade da doença.

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“…A positive tourniquet test in this phase increases the probability of dengue. 7,8 In addition, these clinical features are indistinguishable between severe and nonsevere dengue cases. Therefore monitoring for warning signs and other clinical parameters is crucial to recognizing progression to the critical phase.…”

Section: Febrile Phasementioning

confidence: 99%

Update Management Dengue Shock Syndrome in Pediatric Cases

Soegijanto

Chilvia

2013

IJTID

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Background: Since 1968 Dengue Virus Infection has been found in Indonesia, especially at Surabaya and Jakarta city. Firstly management of dengue virus infection very difficult to improve, therefore the higher mortality nearly 41,4% had been found but on the following years in five decades the mortality rates was becoming to decrease until 1,27% on 2011. Aim: To find the new management of Dengue Shock Syndrome to reach the lower fatality rate below 1%. Method: Until now to manage Dengue Shock Syndrome is very difficult, some cases can be improved but the other lost due to the late coming in the hospital and not involved in criteria diagnosis base on WHO 1997. To solve this problem WHO 2009 had made new criteria diagnosis Dengue Virus Infection focusing on early detection of severe Dengue Virus Infection especially Dengue Shock Syndrome. Result: On 2011 WHO had made an integrated criteria diagnosis base on WHO 2009 and WHO 1997. These criteria was focusing in Update management of Dengue Shock Syndrome in Pediatric Cases. Based on this action, this paper will improve clinical management to reach the lower mortality of Dengue Shock Syndrome in Community until CFR < 1%. Conclusion: By using integrated criteria of WHO 2009 and 1997, update management of Dengue Shock Syndrome in Pediatric cases, can improve clinical management to reach the lower mortality in community until CFR < 1%.

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Evaluation of the World Health Organization standard tourniquet test and a modified tourniquet test in the diagnosis of dengue infection in Viet Nam

Cited by 92 publications

References 9 publications

Evaluation of the diagnostic value of the tourniquet test in predicting severe dengue cases in a population from Belo Horizonte, State of Minas Gerais, Brazil

Evaluation of the diagnostic value of the tourniquet test in predicting severe dengue cases in a population from Belo Horizonte, State of Minas Gerais, Brazil

Alterações hematológicas em pacientes com dengue

Update Management Dengue Shock Syndrome in Pediatric Cases

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