Evaluation of the Usefulness of Virtual Chromoendoscopy with Different Color Modes in the MiroCam® System for Characterization of Small Bowel Lesions

Abstract

Background: Virtual chromoendoscopy (VC) in small bowel capsule endoscopy can improve the visualization and characterization of different small bowel lesions (SBLs). There are few studies of its usefulness in the Given® system, and there is no evidence yet of its utility in the MiroCam® system. Aim: The aim of this study was to evaluate whether VC can improve the characterization of SBLs with the MiroCam® system. Methods: Twenty-two patients were selected, in which 100 elementary lesions were identified, including erosions (n = 45), ulcers (n = 17), and angioectasias (n = 38). For each lesion identified, images were captured without chromoendoscopy (normal image [NI]) and with chromoendoscopy modes 1 (color mode [CM] 1), 2 (CM2), and 3 (CM3). A score from 1 to 4 was assigned to each image, in which a better evaluation of the characteristics and limits of the lesion was classified in ascending order, where 1 is the worst and 4 the best evaluation. The scores of the various modes were compared with Kendall's tau-c coefficient. Results: The average scores attributed to the photographs in NI, CM1, CM2, and CM3 were 3.83, 2.89, 1.85, and 1.43, respectively (tau-c = -0.75, p < 0.001). Evaluating the elementary lesions independently, the average scores for modes NI, CM1, CM2, and CM3 were 3.83, 2.92, 1.86, and 1.38 (tau-c = -0.77, p < 0.001) for erosions, respectively; 3.87, 2.96, 1.76, and 1.40 (tau-c = -0.80, p < 0.001) for ulcers, respectively; and 3.81, 2.82, 1.87, and 1.50 (tau-c = -0.71, p < 0.001) for angioectasias, respectively. Conclusions: VC using the CMs available in the MiroCam® system has not proven useful for a better assessment of any of the SBLs.

Image-Enhanced Capsule Endoscopy Improves the Identification of Small Intestinal Lesions

“…Regarding the MiroCam software (IntroMedic, Soul, Korea), Ryu et al showed that ALICE improved the visibility of flat and depressed small bowel lesions [57]. Ribeiro et al [58] reported that another IEE system that enhances images in 3 color modes (CM 1, CM 2, and CM 3) was not useful to improve the evaluation and characterization of any of the small intestinal lesions. In their study, 22 patients were selected, in whom 100 elementary lesions were identified, including erosions (n = 45), ulcers (n = 17), and angioectasias (n = 38).…”

Clinical Performance of New Software to Automatically Detect Angioectasias in Small Bowel Capsule Endoscopy

“…The Augmented Live-Body Image Color-Spectrum Enhancement (ALICE) chromoendoscopy system was able to enhance GE Port J Gastroenterol 2021;28:87-96 DOI: 10.1159/000510024 the visibility of angioectasias [20]. On contrary, another chromoendoscopy system that enhances the image in 3 color modes (CM1, CM2, and CM3) was not useful to improve evaluation and characterization of any of the elementary lesions [21].…”

Image-Enhanced Small Bowel Capsule Endoscopy: Promises and Caveats

“…In this issue of GE Portuguese Journal of Gastroenterology , Ribeiro da Silva et al [4] present us the first study about the utility – in delineation of lesions – of the 3 “color modes” of the MiroCam System. One hundred elementary lesions (angiectasias, ulcers, and erosions) were scored 1–4 (worst to better) by 6 readers who compared conventional images and the ones provided by each of the color modes.…”