Evaluation of the Tissue Reaction to Fast Endodontic Cement (CER) and Angelus MTA

Gomes‐Filho, João Eduardo; Rodrigues, Guilherme Scopel; Watanabe, Simone; Bernabé, Pedro Felício Estrada; Lodi, Carolina Simonett; Gomes, Alessandra Rodrigues; Faria, Max Doulgas; Santos, Alailson Domingos dos; Moraes, João Carlos Silos

doi:10.1016/j.joen.2009.06.010

Cited by 70 publications

(117 citation statements)

References 22 publications

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“…Among these, MTA, which is also called ProRoot MTA, has been used successfully in endodonctics for the past 10 years. [1][2][3] More recently, new products similar to MTA have been introduced into the market including MTA angelus [4][5][6] and MTAbio 7 (Angelus Solucoes Odontologicas, Londrina, Brazil) and Bioaggregate 8 (Innovative Bioceramix, Vancouver, Canada). Bioaggregate is sold exclusively in Canada.…”

Section: Introductionmentioning

confidence: 99%

Biocompatibility of bioaggregate cement on human pulp and periodontal ligament (PDL) derived cells

Chung

Kim

Shin

2010

J Korean Acad Conserv Dent

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Objectives: This study was performed to investigate the biocompatibility of newly introduced Bioaggregate on human pulp and PDL cells. Materials and Methods: Cells were collected from human pulp and PDL tissue of extracted premolars. Cell culture plate was coated either with Bioaggregate or white MTA, then the same number of cells were poured to cell culture dishes. Cell attachment and growth was examined under a phase microscope after 1,3 and 7 days of seeding. Cell viability was measured and the data was analyzed using Student t-test and one way ANOVA. Results: Both types of cells used in this study were well attached and grew healthy on Bioaggregate and MTA coated culture dishes. No cell inhibition zone was observed in Bioaggregate group. There was no statistical difference of viable cells between bioaggreagte and MTA groups. Conclusions: Bioaggregate appeared to be biocompatible compared with white MTA on human pulp and PDL cells.

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Section: Introductionmentioning

confidence: 99%

Biocompatibility of bioaggregate cement on human pulp and periodontal ligament (PDL) derived cells

Chung

Kim

Shin

2010

J Korean Acad Conserv Dent

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“…17,18 It is known that CER cement releases calcium and hydroxyl ions, and increases the pH of the medium in a manner similar to that of MTA cement. 13 After 24 hours, the calcium and hydroxyl ions released by CER cement are greater than those released by MTA; however, following this initial period, the values become similar.…”

Section: A B C D E Fmentioning

confidence: 99%

“…Since the setting time of the tested cements may extend from 24 hours (initial setting time) up to 7 days (final setting time), the rate of calcium and hydroxyl ions released from the cements may vary significantly, thus allowing for an increase in cement cytotoxicity. 16,17 On the other hand, a previous in vivo study 18 reported a favorable histological response promoted by CER and MTA at the 7-day period. However, it is worthwhile stressing that in vitro conditions are not homeostatic, and that there is no tissue elimination of toxic substances, such as that reported for in vivo assays.…”

mentioning

confidence: 94%

Cytotoxic effects of new MTA-based cement formulations on fibroblast-like MDPL-20 cells

et al. 2016

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The present study aimed at evaluating the cytotoxic effects of a novel cement called CER on periodontal fibroblast-like cells of mice , in comparison with different formulations of Mineral Trioxide Aggregate (MTA), by means of the cell viability test (MTT) and cell morphology analysis. Thirty-two round-shaped samples were fabricated with the following cements: white MTA, white and gray CER and experimental white MTA. The samples were immersed in serum-free culture medium for 24 hours or 7 days (n = 16). The extracts (culture medium + components released from the cements) were applied for 24 hours to previously cultured cells (40.000 cells/cm 2 ) in the wells of 24-well plates. Cells seeded in complete culture medium were used as a negative control. Cell viability was assessed using the MTT assay. Two samples of each cement were used for cell morphology analysis by Scanning Electron Microscopy (SEM). The extracts obtained at the 7-day period presented higher cytotoxicity compared with the 24-hour period (p < 0.05). The gray CER obtained at 24 hours presented the highest cytotoxic effect, whereas the experimental white MTA presented the lowest, similar to the control (p > 0.05). However, at the 7-day period, the experimental white MTA presented no significant difference in comparison with the other cements (p > 0.05). At the 7-day period, CER cement presented cytotoxic effects on fibroblast-like cells, similar to different MTA formulations. However, the immersion period in the culture medium influenced the cytotoxicity of the cements, which was greater for CER cement at 24 hours.

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“…7,8 MTA'nın birçok avantajına rağmen reolojik özellikleri klinik uygulamasını zorlaştırmakta ve yaygın kullanımını sınırlamaktadır. 9 MTA'nın uygulama esnasında periapikal dokulara taşması düşük derecede reaksiyona neden olsa bile kontrollü bir şekilde kullanımı önerilmektedir. 10 İnternal matriks kullanımıyla MTA'nın periapikal bölgeye taşması engellenir, tamir materyalinin sızıntısı azalmakta ve periodontal dokular korunmuş olmaktadır.…”

Section: Introductionunclassified

İnternal matriks ile birlikte kullanılan MTA’nın ortograd ve retrograd uygulanmasının farklı apikal açıklığa sahip dişler üzerindeki güçlendirme etkisinin değerlendirilmesi

Bayram¹,

Bayram²,

Eren³

2015

Acta Odontol Turc

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[Abstract in English is at the end of the manuscript] GİRİŞDişlerin kırılmaya karşı direncini belirleyen en önemli faktörlerin başında dentin kalınlığı gelmektedir. Diş dokularındaki kayıp, dentinin oklüzal veya travmatik kuvvetler karşısındaki elastikiyetini ve direncini etkileyerek dişin kırılma direncini azaltır.1 Açık apeks, kök gelişimini tamamlamamış daimi bir dişte enfeksiyon ya da travmaya bağlı olarak; gelişimini tamamlamış daimi bir dişte ise enfeksiyon sonucunda apikal sement ve dentinin rezorbe olması ile oluşabilmektedir. Apeksifikasyon, açık olan apeksin sert doku engeli ile tamirini hedef alan bir tedavi yöntemidir. Bu işlem, kanalların biyomekanik temizliğini takiben apikal engel oluşmasını ve apikal iyileşmeyi uyarmak veya yardımcı olmak için kanal içi ilaç kullanılmasını gerektirir. Kanal içi ilaç olarak bugüne kadar en sık kalsiyum hidroksit [Ca(OH) 2 ] kullanılmış ve yapılan çalışmalarda oldukça başarılı bulunmuştur. 3,4 Kalsiyum hidroksit ile apeksifikasyon tekniğinin klinik başarısına rağmen, tedavi süresinin değişkenliği, randevu ve alınan radyografi sayısının çokluğu, hasta takibinin güç olması, ertelenen tedaviler ve uzun süre Özgün araştırma makalesiİnternal matriks ile birlikte kullanılan MTA'nın ortograd ve retrograd uygulanmasının farklı apikal açıklığa sahip dişler üzerindeki güçlendirme etkisinin değerlendirilmesi

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Evaluation of the Tissue Reaction to Fast Endodontic Cement (CER) and Angelus MTA

Cited by 70 publications

References 22 publications

Biocompatibility of bioaggregate cement on human pulp and periodontal ligament (PDL) derived cells

Biocompatibility of bioaggregate cement on human pulp and periodontal ligament (PDL) derived cells

Cytotoxic effects of new MTA-based cement formulations on fibroblast-like MDPL-20 cells

İnternal matriks ile birlikte kullanılan MTA’nın ortograd ve retrograd uygulanmasının farklı apikal açıklığa sahip dişler üzerindeki güçlendirme etkisinin değerlendirilmesi

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