Evaluation of the Quantitative Direct Antiglobulin Test in Hemolytic Disease of the Newborn Due to Anti-D

Abstract

1. 86 infants with hemolytic disease due to anti-D iso-immunization were studied by the quantitative direct antiglobulin test. 2. No regular correlation was found between this test and clinical severity.

Antibodies, antigens, and anticoagulants: a historical review of a lifetime in transfusion medicine—the Landsteiner Lecture 2004

“…I wanted to do a PhD in biochemistry, but in those days you could not take it part time. We did a lot of biochemical studies in the 1950s and 1960s, including further studies on HDN 39‐50 . One of my associates, Sam Morell, was an expert on adenosine triphosphate (ATP) and had experience isolating nucleotides and coenzymes.…”

“…We did a lot of biochemical studies in the 1950s and 1960s, including further studies on HDN. [39][40][41][42][43][44][45][46][47][48][49][50] One of my associates, Sam Morell, was an expert on adenosine triphosphate (ATP) and had experience isolating nucleotides and coenzymes. I was very interested to learn why there was so much 2,3-diphosphoglycerate acid (2,3-DPG) in the RBC.…”