Evaluation of the potential of chimeric spidroins/poly(L-lactic-co-ε-caprolactone) (PLCL) nanofibrous scaffolds for tissue engineering

Preparation of controlled degradation of insulin-like growth factor 1/spider silk protein nanofibrous membrane and its effect on endothelial progenitor cell viability

“…These main peaks indicated the amide I and II bands which were the key functional groups of protein. The analysis results of FTIR showed that the secondary structure contents in the fiber was quite different from spinning dope with decreased α-helix and increased β-sheet, indicating an α-helix to β-sheet transformation during spinning process, which was in line with the previous reports on the secondary structure changes during the wet-spinning process [ 37 , 38 ] and electro-spinning process [ 39 ]. For silk fibers, β-sheet structure provides the strength of mechanical performance.…”

Defining the regenerative effects of native spider silk fibers on primary Schwann cells, sensory neurons, and nerve‐associated fibroblasts

“…46,60 With respect to future biomedical applications, current research is focusing on the controlled production of silk fibers, for example, derived from recombinant silk proteins. [60][61][62][63][64] The ultimate goal is to create a recombinant silk fiber that emulates the peerless properties of its native counterpart. Recombinant silk shall not only possess the unique material characteristics, but also show the same (or superior) effect on cells.…”

“…Recombinant silk shall not only possess the unique material characteristics, but also show the same (or superior) effect on cells. Previous studies suggest different methods to analyze the behavior of cells to silk fibers 57,63,[65][66][67] or silk-based materials 68,69 in vitro. However, quantitative and qualitative read-outs designed to assess the biological response of cells to silk fibers concerning nerve tissue regeneration are scarce.…”

Construction of Stretchable and Large Deformation Green Triboelectric Nanogenerator and Its Application in Technical Action Monitoring of Racket Sports

“…As the results show, pure PLCL presented a relatively obvious absorption peak at 2942 cm –1 , which corresponds to the −CH 2 – stretching group in the molecular skeleton of PLCL. − In addition, with the increase of PLCL contents, the absorption peak of the −CH 2 – stretching group gradually widened. Due to the stretching vibration of the −CO– bond of the carbonyl group, the PHB membranes, the PHB/PLCL composite membranes, and the PLCL membranes had strong characteristic absorption peaks of −CO– in the region between 1700 and 1793 cm –1 . ,, The vibration absorption peak of −C–H– appeared at 1454 cm –1 , and that of −C–O– appeared at 1084 cm –1 . The absorption peak became significantly larger with the increase of PLCL contents.…”