Evaluation of the polycaprolactone (PCL) hydrolytic degradation in acid solvent and its influence on the electrospinning process
Javier Mauricio Anaya-Mancipe,
Agnes Chacor Figueirdo,
Lucas Gomes Rabello
et al.
Abstract:Poly(ε-caprolactone) (PCL) is one of the most widely used biopolymers in biomedicine for the production of scaffolds and biomaterials in tissue engineering. This is due to its characteristics as a drug carrier, as well as excellent controlled release properties compared to other biopolymers. Electrospinning is a technique often employed for manufacturing mats with this application, although chlorinated or fluorinated solvents are predominantly used, presenting high cellular toxicity. A viable alternative as a … Show more
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