Evaluation of the Parasympathetic Tone Activity (PTA) index to assess the analgesia/nociception balance in anaesthetised dogs

Mansour, Christelle; Merlin, Tristan; Bonnet-Garin, Jeanne-Marie; Chaaya, Rana; Mocci, Rita; Ruiz, Clara Conde; Allaouchiche, Bernard; Boselli, Emmanuel; Junot, Stéphane

doi:10.1016/j.rvsc.2017.05.009

Cited by 36 publications

(92 citation statements)

References 29 publications

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“…Surgical stimuli such as clamping the surgical drapes to the skin and surgical skin incision produced a decrease in PTA values (24% and 32%, respectively) 5 minutes later. However, the maximum increases in HR (10%) and BP (14%) were not considered to be clinically relevant although they were statistically significant (Mansour et al 2017). These cardiovascular changes may indicate a response to the medium-intensity nociceptive stimuli observed in our study.…”

Section: Discussionmentioning

confidence: 59%

“…A recent clinical study evaluated the PTA monitor in anaesthetized healthy dogs undergoing different types of surgery: arthroscopy, castration, ovariectomy or cutaneous mass excision (Mansour et al 2017). Surgical stimuli such as clamping the surgical drapes to the skin and surgical skin incision produced a decrease in PTA values (24% and 32%, respectively) 5 minutes later.…”

Section: Discussionmentioning

confidence: 99%

“…The principles underlying the function of the PTA monitor have been described previously (Jeanne et al 2009;Logier et al 2010;Mansour et al 2017). But briefly, the PTA monitor detects R waves from the ECG and calculates RR intervals with an accuracy of ± 4 ms.…”

Section: Anaesthetic Protocolmentioning

confidence: 99%

“…( 1)Both a and b have been determined to provide consistency between the visual effect of respiration influence on the RR series and the PTA index value. The dog's specific coefficient is 100/161 (Mansour et al 2017). The PTA monitor displays two variables: the 'immediate' PTA, which indicates the PTA index calculated from the 54 previous values updated every second.…”

Section: Anaesthetic Protocolmentioning

confidence: 99%

“…The ANI monitor has been adapted for use in veterinary patients and called a Parasympathetic Tone Activity monitor (PTA) (PhysioDoloris; Mdoloris Medical Systems, France). The first clinical study in dogs reported a decrease in PTA values, at 1 and 5 minutes after the application of surgical drapes to the skin and surgical skin incision, associated with an increase in BP and HR (Mansour et al 2017). However, no studies determined whether the PTA monitor could identify more subtle changes in nociception that did not elicit a cardiovascular response.…”

Section: Introductionmentioning

confidence: 99%

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Efficacy of the Parasympathetic Tone Activity monitor to assess nociception in healthy dogs anaesthetized with propofol and sevoflurane

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Section: Discussionmentioning

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Section: Anaesthetic Protocolmentioning

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confidence: 99%

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The combination of an ultrasound‐guided erector spinae plane (ESP) block and epidural morphine as effective intra‐operative adjuncts to opioid premedication in six dogs undergoing lateral thoracotomy

Fernández

Huuskonen

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2021

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Six dogs were presented to the University College Dublin Veterinary Hospital for either left or right lateral thoracotomy. After opioid premedication and induction of general anaesthesia, ultrasound-guided erector spinae plane (ESP) block with bupivacaine 0.5% (0.5 mL/kg) or bupivacaine 0.25% (1 mL/kg) was performed in all cases before the surgical procedure along with morphine (0.2 mg/kg) administered epidurally. This combination of local techniques was a successful adjunct to systemic analgesia in these six dogs undergoing lateral thoracotomy, reducing considerably the need for systemic opioids intra-and post-operatively. Ultrasound-guided ESP block with bupivacaine and epidurally administered morphine provided good multimodal intra-operative analgesia for dogs undergoing lateral thoracotomy. BACKGROUNDLateral thoracotomy is one of the most painful but commonly performed surgical procedure to manage diseases within the thoracic cavity in small animals. 1,2 In humans it is known that adequate intra-and post-operative analgesia is essential to allow for early mobilization and discharge and also to reduce the incidence of chronic neuropathic pain development. [3][4][5][6] In human and veterinary medicine, both systemic administration of opioids and locoregional anaesthesia have been used to manage intra-and post-operative pain after lateral thoracotomy. 3,7,8 The use of locoregional anaesthesia reduces systemic opioid requirement and provides analgesia without central respiratory depression or sedation, thus improving ventilation and allowing a more accurate clinical assessment of the patient. 9,10 Thoracic epidural catheter is the "gold standard" analgesic technique in humans, 11 and its effectiveness in providing analgesia in lateral thoracotomies has also been reported in veterinary medicine. 12,13 However, the technique itself and the epidural administration of local anaesthetics may have certain complications and contraindications. 12,14,15 In dogs, these can include mechanical or chemical injury of the spinal cord, motor function impairment, and sympathetic blockade leading to hypotension. 12 Vomiting has also beenThis is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

show abstract

Evaluation of the Parasympathetic Tone Activity (PTA) index to assess the analgesia/nociception balance in anaesthetised dogs

Cited by 36 publications

References 29 publications

Efficacy of the Parasympathetic Tone Activity monitor to assess nociception in healthy dogs anaesthetized with propofol and sevoflurane

Efficacy of the Parasympathetic Tone Activity monitor to assess nociception in healthy dogs anaesthetized with propofol and sevoflurane

Heart Rate Variability

The combination of an ultrasound‐guided erector spinae plane (ESP) block and epidural morphine as effective intra‐operative adjuncts to opioid premedication in six dogs undergoing lateral thoracotomy

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