Evaluation of the occurrence of metabolic syndrome in obese dogs and the role of caloric restriction diet as an adjuvant therapy

Abstract

Metabolic syndrome, or metabolic dysfunction related to obesity in dogs, is a set of factors that may predispose comorbidities secondary to obesity. Adjuvant therapy with an energy-restricted diet, especially with low levels of carbohydrate and fat, is essential for weight loss, in addition to controlling snacks intake. The aim of this study was to evaluate the biochemical profile of obese dogs compared to lean dogs, and also to compare these profiles before and after a 30-day treatment, thus evaluating the possibility of obesity-related metabolic dysfunction and the action of adjuvant dietary therapy in this condition. Cholesterol and its fractions (HDL, LDL and VLDL), triglycerides, systemic blood pressure and glycemia of obese and lean dogs were measured, and seven obese dogs were treated only with a low-calorie diet with low levels of fat and carbohydrates for 30 days; these patients were evaluated before and after treatment. Obese dogs showed higher levels of triglycerides than lean dogs, and dogs treated with low-calorie diet presented weight loss and better outcomes related to biochemical profile, especially triglycerides levels, after treatment.

Evaluación del perfil lipídico y niveles de glucosa en perros obesos

“…El perfil lipídico y los niveles de glucosa juegan un papel crucial en la comprensión de las alteraciones metabólicas en perros obesos. Los estudios han demostrado que los perros obesos presentan niveles más altos de triglicéridos, colesterol y aminoácidos de cadena ramificada, lo que indica una desregulación metabólica ( (Vendramini et al, 2021), (Fernandes et al, 2022), (Feitosa et al, 2016). Además, la hiperglucemia y la hiperlipidemia son trastornos de salud comunes asociados con la obesidad en los perros, y las respuestas glucémicas están influenciadas por el tipo de almidón consumido (de Marchi et al, 2020).…”