Evaluation of the novel coronavirus disease in Turkish Children; Preliminary Outcomes

Yılmaz, Kamil; Pirinççioğlu, Ayfer Gözü; Aktar, Fesih; Akın, Alper; Karabel, Müsemma; Yolbaş, İlyas; Ertuğrul, Sabahattin; Üzel, Veysiye Hülya; Ünal, Edip; Deger, İbrahim; Toy, Kadri; Zan, Hasan; Onder, Cihan; Tekin, Recep; Mermutluoğlu, Çiğdem; Yilmaz, Evre; Şen, Hadice Selimoğlu; Yılmaz, Süreyya; Özmen, Cihan Akgül; Şen, Velat; Yilmaz, Zulfikar

doi:10.22541/au.159466822.20489043

Cited by 1 publication

(3 citation statements)

References 15 publications

(24 reference statements)

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“…Although COVID-19 disease has a milder course in children than adults, there are also severe pediatric presentations. 4,21 20 Our results support this view.…”

Section: Ta B L E 4 Comparison Of Laboratory Findings Between Covid 19 and Influenza Patientssupporting

confidence: 88%

“…Although COVID‐19 disease has a milder course in children than adults, there are also severe pediatric presentations 4,21 . Changes in acute phase reactants in the course of many diseases are carefully monitored by clinical physicians.…”

Section: Discussionmentioning

confidence: 99%

“…Many studies have shown that COVID‐19 disease may have a milder or asymptomatic course in children compared to adults 4 . Of note, however, the number of Multisystem Inflammatory syndrome in Children (MIS‐C) cases that develop after SARS‐Cov‐2 infection has started to increase gradually 5 .…”

Section: Introductionmentioning

confidence: 99%

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Does Covid‐19 in children have a milder course than Influenza?

et al. 2021

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Background In December 2019, a novel type of coronavirus infection emerged in the Wuhan province of China and began to spread rapidly. In this study, we aimed to determine the differences between COVID‐19 disease and Influenza. Methods This retrospective study included 164 children with COVID‐19, as well as 46 children with Influenza. The two groups were compared with respect to clinical and laboratory parameters and the rates of intensive care and mechanical ventilation requirement. Results In both groups, the most common admission complaints were fever and cough. As compared to the COVID‐19 group, the Influenza group had significantly higher rates of cough (37 [80.4%] and 38 [23.2%]), fever (31 [67.4%] and 34 [20.7%]), muscle pain (34 [73.9%] and 31 [18.9%]), vomiting (13 [28.9%] and 8 [4.9%]) and tachypnea (32 [69.6%] and 3 [1.8%]) ( P < .01 for all comparisons). The mean WBC count (7.10 ± 1.08 vs. 10.90 ± 1.82), mean neutrophil count (3.19 ± 0.58 vs. 6.04 ± 0.97), APTT, CRP, procalcitonin, ALT, and LDH levels were significantly lower in the COVID‐19 group compared to the Influenza group ( P < .05 for all comparisons). There was, however, no significant difference between the mean lymphocyte counts of both groups. The Influenza group had significantly higher rates of intensive care requirement (19 [41.3%] vs. 3 [1.8%]) and mechanical ventilation requirement (16 [34.8%] vs. 2 [1.2%]) as well as a significantly higher mortality rate (7 [15.2%] vs. 2 [1.2%]) than the COVID‐19 group ( P < .01). Conclusion COVID‐19 and Influenza may share similar clinical features. According to our findings, however, we believe that COVID‐19 disease has a milder clinical and laboratory course than Influenza in children.

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“…Although COVID-19 disease has a milder course in children than adults, there are also severe pediatric presentations. 4,21 20 Our results support this view.…”

Section: Ta B L E 4 Comparison Of Laboratory Findings Between Covid 19 and Influenza Patientssupporting

confidence: 88%

Section: Discussionmentioning

confidence: 99%