Evaluation of the mechanical properties of powder metallurgy Ti-6Al-7Nb alloy

Bolzoni, Leandro; Ruiz-Navas, E.M.; Gordo, E.

doi:10.1016/j.jmbbm.2016.12.005

Cited by 44 publications

(12 citation statements)

References 17 publications

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“…Titanium substrates for microbiological studies were prepared by a conventional powder metallurgy route applying a cold uniaxial charge of 7.9 tn/cm 2 followed by a sintering step at 1,250 • C for 120 min under high vacuum (10 −5 mbar), as described elsewhere by Bolzoni et al (2017). The starting Ti powders with a particle size below 75 µm were supplied by AP&C Inc., (Canada).…”

Section: Materials Synthesismentioning

confidence: 99%

A New Antibiotic-Loaded Sol-Gel Can Prevent Bacterial Prosthetic Joint Infection: From in vitro Studies to an in vivo Model

et al. 2020

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The aim of this study was to evaluate the effect of a moxifloxacin-loaded organicinorganic sol-gel with different antibiotic concentration in the in vitro biofilm development and treatment against Staphylococcus aureus, S. epidermidis, and Escherichia coli, cytotoxicity and cell proliferation of MC3T3-E1 osteoblasts; and its efficacy in preventing the prosthetic joint infection (PJI) caused by clinical strains of S. aureus and E. coli using an in vivo murine model. Three bacterial strains, S. epidermidis ATCC 35984, S. aureus 15981, and, E. coli ATCC 25922, were used for microbiological studies. Biofilm formation was induced using tryptic-soy supplemented with glucose for 24 h, and then, adhered and planktonic bacteria were estimated using drop plate method and absorbance, respectively. A 24-h-mature biofilm of each species growth in a 96well plate was treated for 24 h using a MBECTM biofilm Incubator lid with pegs coated with the different types of sol-gel, after incubation, biofilm viability was estimated using alamrBlue. MC3T3-E1 cellular cytotoxicity and proliferation were evaluated using CytoTox 96 Non-Radioactive Cytotoxicity Assay and alamarBlue, respectively. The microbiological studies showed that sol-gel coatings inhibited the biofilm development and treated to a mature biofilm of three evaluated bacterial species. The cell studies showed that the sol-gel both with and without moxifloxacin were non-cytotoxic and that cell proliferation was inversely proportional to the antibiotic concentration containing by sol-gel. In the in vivo study, mice weight increased over time, except in the E. coliinfected group without coating. The most frequent symptoms associated with infection were limping and piloerection; these symptoms were more frequent in infected groups

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Section: Materials Synthesismentioning

confidence: 99%

A New Antibiotic-Loaded Sol-Gel Can Prevent Bacterial Prosthetic Joint Infection: From in vitro Studies to an in vivo Model

et al. 2020

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“…Additives of Mo, Ta, and Nb stabilize the β-phase and improve their fatigue strength, corrosion resistance, and elastic modulus, which should be similar to the elastic modulus of human bone [5,6]. However, due to their high production costs, their involvement in medical applications is limited [7,8]. Moreover, the majority of titanium alloys contain aluminum as an alloying agent, the ions of which damage nerve cells and block the bonding of proteins responsible for their regeneration.…”

Section: Introductionmentioning

confidence: 99%

Fretting and Fretting Corrosion Processes of Ti6Al4V Implant Alloy in Simulated Oral Cavity Environment

2020

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The paper presents the results of in vitro studies of fretting and fretting corrosion processes of Ti6Al4V implant alloy in the environment of natural saliva and self-made mucin-based artificial saliva solutions. The study was performed on a specially designed fretting pin-on-disc tester, which was combined with a set used for electrochemical research. The open circuit potential measurements and potentiodynamic method were used for corrosion tests. The worn surfaces were subjected to microscopic observations and an evaluation of wear. Results were interpreted using the dissipated energy and third-body approaches. The X-ray diffraction analysis showed that titanium oxides constitute over 80% of the friction products. Special attention was paid to the role of saliva and its substitutes, which in certain cases can lead to the intensification of fretting wear. On the basis of the received results, a new phenomenological model of fretting corrosion processes was proposed. This model involves the formation of an abrasive paste that is a combination of metal oxides and the organic components of saliva.

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“…Using raw powders to prepare the titanium alloy products instead of conventional melting and casting is proved as a feasible method with the economic benefits. Powder metallurgy (PM) titanium alloys parts can be produced through hot isostatic pressing, vacuum sintering and selective melting with qualified properties and refined microstructures 5,6 . In order to reduce the cost further and shorten the manufacturing period, fast consolidation approaches have been developed by the researchers like power forging and hot pressing 7,8 .…”

Section: Introductionmentioning

confidence: 99%

Effect of Processing Parameters on Hot Deformation Behaviour and Microstructural Evolution of PM Ti-5553 Alloy at a Moderate-high Strain Rate

et al. 2019

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Isothermal compression tests of Ti-5553 (Ti-5Al-5V-5Mo-3Cr) alloy, produced by a fast consolidation approach from blended elemental powder mixture, were performed on a Gleeble ® 3800 thermal-physical simulator to investigate its hot deformation behaviour. The samples were compressed in a wide temperature range from 700 °C to 1150 °C and a moderate-high strain rate of 1 s -1 , with the sample deformation degree of 30%, 50% and 70%, respectively. Flow instability occurred when the deformation temperature was less than 900 °C. Dynamic recovery (DRV) accompanied by dynamic recrystallization (DRX) become the dominated mechanisms at the medium temperature range between 900 °C and 1000 °C, while almost only DRV features could be observed at high temperature (1050 °C ~ 1150 °C). Moreover, α phase globalization could be identified in the alloy deformed in (α+β) region. DRV, DRX, α globalization and the transformation of α to β phase were promoted with the increasing deformation degree.

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Evaluation of the mechanical properties of powder metallurgy Ti-6Al-7Nb alloy

Cited by 44 publications

References 17 publications

A New Antibiotic-Loaded Sol-Gel Can Prevent Bacterial Prosthetic Joint Infection: From in vitro Studies to an in vivo Model

A New Antibiotic-Loaded Sol-Gel Can Prevent Bacterial Prosthetic Joint Infection: From in vitro Studies to an in vivo Model

Fretting and Fretting Corrosion Processes of Ti6Al4V Implant Alloy in Simulated Oral Cavity Environment

Effect of Processing Parameters on Hot Deformation Behaviour and Microstructural Evolution of PM Ti-5553 Alloy at a Moderate-high Strain Rate

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